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Publications

Protocol to profile spatially resolved NLRP3 inflammasome complexes using APEX2-based proximity labeling

Liang Z. et al, (2024), STAR Protocols, 5, 103417 - 103417

Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L

Zhu K. et al, (2024), EMBO Reports

Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair

Yang H. et al, (2024), Science Advances, 10

Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients

Stieger A. et al, (2024), Metabolites, 14, 334 - 334

Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank.

Lassen FH. et al, (2024), Cell genomics

Deubiquitinases in muscle physiology and disorders.

Olie CS. et al, (2024), Biochem Soc Trans

HSV-1 employs UL56 to antagonize expression and function of cGAMP channels

Blest HTW. et al, (2024), Cell Reports, 43, 114122 - 114122

Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.

Ellis MJ. et al, (2024), Acta neuropathologica, 147

Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex

Damianou A. et al, (2024), Life Science Alliance, 7, e202302245 - e202302245

Quantitative proteomics reveals CLR interactome in primary human cells

Manolis D. et al, (2024), Journal of Biological Chemistry, 107399 - 107399

A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology

Pisa M. et al, (2024), Brain Pathology

Type I interferon regulation by USP18 is a key vulnerability in cancer

Jové V. et al, (2024), iScience, 27

Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia.

Liang Z. et al, (2024), Cell reports, 43

Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity

Hamid MHBA. et al, (2024), Nature Immunology

Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1

Imhoff RD. et al, (2024), Journal of Medicinal Chemistry, 67, 4496 - 4524

BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution

Tsukada K. et al, (2024), Molecular Cell, 84, 640 - 658.e10

Data‐independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis

Dellar ER. et al, (2024), Journal of Neurochemistry, 168, 115 - 127

Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors

Lo Faro ML. et al, (2024), Kidney International Reports

Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model

van Leeuwen LL. et al, (2024), British Journal of Pharmacology, 181, 464 - 479

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism

Gan J. et al, (2023), Proceedings of the National Academy of Sciences, 120

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