Integrative proximal-ubiquitomics profiling for deubiquitinase substrate discovery applied to USP30
Damianou A. et al, (2025), Cell Chemical Biology
Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium
Smith C. et al, (2025), PLOS Pathogens, 21, e1013032 - e1013032
Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
Scott HC. et al, (2025), Journal of Endocrinology and Metabolism, 15, 1 - 14
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2
Li HZ. et al, (2025), Nature Communications, 16
Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor
O’Brien DP. et al, (2025), Journal of Proteome Research
USP4 Auto-Deubiquitylation Promotes Homologous Recombination.
Wijnhoven P. et al, (2025), Molecular cell
Protocol to profile spatially resolved NLRP3 inflammasome complexes using APEX2-based proximity labeling
Liang Z. et al, (2024), STAR Protocols, 5, 103417 - 103417
Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L
Zhu K. et al, (2024), EMBO Reports
Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair
Yang H. et al, (2024), Science Advances, 10
Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank.
Lassen FH. et al, (2024), Cell genomics, 4
Deubiquitinases in muscle physiology and disorders
Olie CS. et al, (2024), Biochemical Society Transactions, 52, 1085 - 1098
Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients
Stieger A. et al, (2024), Metabolites, 14, 334 - 334
HSV-1 employs UL56 to antagonize expression and function of cGAMP channels
Blest HTW. et al, (2024), Cell Reports, 43, 114122 - 114122
Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
Ellis MJ. et al, (2024), Acta neuropathologica, 147
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex
Damianou A. et al, (2024), Life Science Alliance, 7, e202302245 - e202302245
Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia
Liang Z. et al, (2024), Cell Reports, 43, 114152 - 114152
Quantitative proteomics reveals CLR interactome in primary human cells
Manolis D. et al, (2024), Journal of Biological Chemistry, 107399 - 107399
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
Hamid MHBA. et al, (2024), Nature Immunology, 25, 834 - 846
A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology
Pisa M. et al, (2024), Brain Pathology