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Publications

Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.

Carroll TM. et al, (2023), Cancer cell, 41, 1222 - 1241.e7

Disparities in care and outcomes for primary liver cancer in England during 2008-2018: a cohort study of 8.52 million primary care population using the QResearch database.

Liao W. et al, (2023), EClinicalMedicine, 59

Cell-free DNA TAPS provides multimodal information for early cancer detection.

Siejka-Zielińska P. et al, (2021), Science advances, 7

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution

Louphrasitthiphol P. et al, (2020), Molecular Cell, 79, 472 - 487.e10

Cytosine Methylation Affects the Mutability of Neighbouring Nucleotides in Germline and Soma

Kusmartsev V. et al, (2020), Genetics, genetics.303028.2020 - genetics.303028.2020

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution.

Liu Y. et al, (2019), Nature biotechnology, 37, 424 - 429

Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands

Owen RP. et al, (2018), Nature Communications, 9

Mutational signature distribution varies with DNA replication timing and strand asymmetry.

Tomkova M. et al, (2018), Genome Biol, 19

DNA Modifications: Naturally More Error Prone?

Tomkova M. and Schuster-Böckler B., (2018), Trends Genet, 34, 627 - 638

The effects of mutational processes and selection on driver mutations across cancer types

Temko D. et al, (2018), Nature Communications, 9

Erratum to "DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine"[DNA Repair, 62 (2018) 1-7].

Tomkova M. et al, (2018), DNA Repair (Amst), 65

BEARscc determines robustness of single-cell clusters using simulated technical replicates.

Severson DT. et al, (2018), Nat Commun, 9

DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine.

Tomkova M. et al, (2018), DNA Repair (Amst), 62, 1 - 7

Cancer Genetics May Aid Diagnostics of Developmental Disorders.

Zak J. et al, (2016), Hum Mutat, 37

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

Bardella C. et al, (2016), Cancer Cell, 30, 578 - 594

5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA.

Tomkova M. et al, (2016), Elife, 5

The importance of p53 pathway genetics in inherited and somatic cancer genomes

Stracquadanio G. et al, (2016), Nature Reviews Cancer, 16, 251 - 265

Chromatin organization is a major influence on regional mutation rates in human cancer cells.

Schuster-Böckler B. and Lehner B., (2012), Nature, 488, 504 - 507

Dosage sensitivity shapes the evolution of copy-number varied regions.

Schuster-Böckler B. et al, (2010), PLoS One, 5

Large-scale screening for novel low-affinity extracellular protein interactions.

Bushell KM. et al, (2008), Genome Res, 18, 622 - 630

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