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Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase.

Journal article

Kozlova A. et al, (2021), Journal of medicinal chemistry, 64, 10967 - 10980

Arid5a: A Missing Link between EMT and Tumoral Immune Resistance

Journal article

Van den Eynde BJ., (2021), Cancer Immunology Research

Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase

Journal article

Klaessens S. et al, (2021), Proceedings of the National Academy of Sciences, 118, e2022447118 - e2022447118

IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines.

Journal article

Levy T. et al, (2021), Bioorganic & medicinal chemistry letters, 40

TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism

Journal article

Canè S. et al, (2021), Journal for ImmunoTherapy of Cancer, 9, e001798 - e001798

Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins

Journal article

Abi Habib J. et al, (2020), Scientific Reports, 10

Preclinical murine tumor models: a structural and functional perspective

Journal article

Guerin MV. et al, (2020), eLife, 9

Is There a Clinical Future for IDO1 Inhibitors After the Failure of Epacadostat in Melanoma?


Van den Eynde BJ. et al, (2020), ANNUAL REVIEW OF CANCER BIOLOGY, VOL 4, 4, 241 - 256

Inhibition of tryptophan-dioxygenase activity increases the antitumor efficacy of immune checkpoint inhibitors

Journal article

Schramme F. et al, (2019), Cancer Immunology Research, canimm.0041.2019 - canimm.0041.2019

NO• /RUNX3/Kynurenine Metabolic Signaling Enhances Disease Aggressiveness in Pancreatic Cancer.

Journal article

Wang L. et al, (2019), International journal of cancer

Understanding the tumor immune escape and the immune modulatory function of cancer stem cells

Conference paper

Zhu J. et al, (2019), EUROPEAN JOURNAL OF IMMUNOLOGY, 49, 1243 - 1243

Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism.

Journal article

Zhu J. et al, (2019), Cancer Immunol Immunother, 68, 835 - 847

The Vacuolar Pathway of Long Peptide Cross-Presentation Can Be TAP Dependent.

Journal article

Ma W. et al, (2019), J Immunol, 202, 451 - 459

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