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Publications

Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system.

Chen J. et al, (2020), EMBO J

SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020

Lumley SF. et al, (2020), Eurosurveillance, 25

Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison

Ainsworth M. et al, (2020), The Lancet Infectious Diseases

Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

Eyre DW. et al, (2020), eLife, 9

Hepatitis B virus resistance to tenofovir: fact or fiction? A systematic literature review and structural analysis of drug resistance mechanisms

Mokaya J. et al, (2020), Wellcome Open Research, 5, 151 - 151

MichelaNglo: sculpting protein views on web pages without coding.

Ferla MP. et al, (2020), Bioinformatics (Oxford, England), 36, 3268 - 3270

Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.

Curran PR. et al, (2020), Journal of chemical information and modeling, 60, 1911 - 1916

Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al.

Aungier S. et al, (2020), Annals of the rheumatic diseases, 79

What fragment hit to follow and how? Using hotspots to prioritise chemistry resources

Smilova M. et al, (2019), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 258

UbiHub: a data hub for the explorers of ubiquitination pathways.

Liu L. et al, (2019), Bioinformatics (Oxford, England), 35, 2882 - 2884

A genetics-led approach defines the drug target landscape of 30 immune-related traits

Fang H. et al, (2019), Nature Genetics, 51, 1082 - 1091

Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?

Aungier SR. et al, (2019), Annals of the rheumatic diseases, 78, 186 - 191

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

D'Ascenzio M. et al, (2019), Angewandte Chemie International Edition, 58, 1007 - 1012

SATurn: a modular bioinformatics framework for the design of robust maintainable web-based and standalone applications

Damerell DR. et al, (2019), Bioinformatics, 35, 349 - 351

Donated chemical probes for open science

Müller S. et al, (2018), eLife, 7

Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers

Zuliani-Alvarez L. et al, (2017), Nature Communications, 8

The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

Bradley AR. et al, (2017), Essays in Biochemistry, 61, 495 - 503

Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3

Chanalaris A. et al, (2017), Molecular Pharmacology, 92, 459 - 468

Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites

Pearce NM. et al, (2017), Structural Dynamics, 4, 032104 - 032104

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

Pearce NM. et al, (2017), Nature Communications, 8

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