Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Cruz-Migoni A. et al, (2019), Proceedings of the National Academy of Sciences of the United States of America, 116, 2545 - 2550
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment
Quevedo CE. et al, (2018), Nature Communications, 9
BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions
Bery N. et al, (2018), eLife, 7
Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein
Bao L. et al, (2017), Scientific Reports, 7
Abstract LB-068: From intracellular antibody fragments to small molecule inhibitors of mutant KRAS
Quevedo CE. et al, (2017), Cancer Chemistry
Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family
Bataille CJR. et al, (2017), Bioorganic & Medicinal Chemistry, 25, 2657 - 2665
A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1
Laurieri N. et al, (2013), PLoS ONE, 8, e70600 - e70600
A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
Ewan K. et al, (2010), Cancer Research, 70, 5963 - 5973
Microwave-assisted synthesis of 2-aminonicotinic acids by reacting 2-chloronicotinic acid with amines
Quevedo CE. et al, (2009), Tetrahedron Letters, 50, 2481 - 2483
Thermal Elimination of Diethyldithiocarbamates and Application in the Synthesis of (±)-Ferrugine
Ahmed S. et al, (2008), The Journal of Organic Chemistry, 73, 8116 - 8119