Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
Journal article
Barrett JR. et al, (2021), Nature Medicine, 27, 279 - 288
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
Journal article
Ewer KJ. et al, (2021), Nature Medicine, 27, 270 - 278
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
Journal article
Voysey M. et al, (2021), The Lancet, 397, 99 - 111
Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis.
Journal article
Mandriota SJ. et al, (2020), International journal of molecular sciences, 21
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
Journal article
Ramasamy MN. et al, (2020), The Lancet, 396, 1979 - 1993
Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma.
Journal article
Tamura N. et al, (2020), Cancer research
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.
Journal article
Yeow ZY. et al, (2020), Nature, 585, 447 - 452
ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
Journal article
Wells D. et al, (2020), eLife, 9
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
Journal article
Folegatti PM. et al, (2020), The Lancet, 396, 467 - 478
The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates
Journal article
Hinch AG. et al, (2020), Molecular Cell, 79, 689 - 701.e10
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.
Journal article
Nelson L. et al, (2020), Nature communications, 11
CRISPR-Cas9 Causes Chromosomal Instability and Rearrangements in Cancer Cell Lines, Detectable by Cytogenetic Methods.
Journal article
Rayner E. et al, (2019), The CRISPR journal
ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair
Journal article
Wells D. et al, (2019)
The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): Revised characterisation of cytogenetic features.
Journal article
Ragusa D. et al, (2019), Cancer reports (Hoboken, N.J.), 2
Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization.
Journal article
Rudzka DA. et al, (2019), J Cell Sci, 132
The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.
Journal article
Gdula MR. et al, (2019), Nat Commun, 10
The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α.
Journal article
Simões-Sousa S. et al, (2018), Cell Rep, 25, 749 - 760.e6
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
Journal article
Ghezraoui H. et al, (2018), Nature, 560, 122 - 127
PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions
Journal article
Wilson RHC. et al, (2017), DNA Repair, 50, 22 - 35
Repo-Man/PP1 regulates heterochromatin formation in interphase.
Journal article
de Castro IJ. et al, (2017), Nat Commun, 8