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Publications

Ethnic Prevalence of Angiotensin-Converting Enzyme Deletion (D) Polymorphism and COVID-19 Risk: Rationale for Use of Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers.

Sarangarajan R. et al, (2020), Journal of racial and ethnic health disparities

Preclinical drug studies in MEN1-related neuroendocrine neoplasms (MEN1-NENs).

Grozinsky-Glasberg S. et al, (2020), Endocrine-related cancer, 27, R345 - R355

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells

Lines KE. et al, (2020), Endocrine-Related Cancer, 27, 163 - 174

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function

Fagan V. et al, (2019), Journal of Medicinal Chemistry

A genetics-led approach defines the drug target landscape of 30 immune-related traits

Fang H. et al, (2019), Nature Genetics, 51, 1082 - 1091

Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy.

Wu X. et al, (2019), Prostate

ANGIOTENSIN 2 TYPE 2 RECEPTOR BLOCKADE IS A NOVEL TARGET FOR MURINE OSTEOARTHRITIS PAIN

von Loga IS. et al, (2019), OSTEOARTHRITIS AND CARTILAGE, 27, S420 - S421

Organizational innovation for developing new medicines that target aging and age-related conditions.

Ford GA. et al, (2019), J Gerontol A Biol Sci Med Sci

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

D'Ascenzio M. et al, (2019), Angewandte Chemie International Edition, 58, 1007 - 1012

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors

Vazquez‐Rodriguez S. et al, (2019), Angewandte Chemie International Edition, 58, 515 - 519

Donated chemical probes for open science

Müller S. et al, (2018), eLife, 7

BROMODOMAIN INHIBITORS ARE POTENT EPIGENETIC REGULATORS OF CATABOLIC GENE EXPRESSION IN HUMAN OSTEOARTHRITIC CHONDROCYTES

de Andres MC. et al, (2018), OSTEOARTHRITIS AND CARTILAGE, 26, S154 - S154

Therapeutics discovery: From bench to first in-human trials.

Al-Hujaily EM. et al, (2018), Biomed Rep, 8, 275 - 282

Open innovation in neuroscience research and drug discovery

Hunter AJ. et al, (2018), Brain and Neuroscience Advances, 2, 239821281879927 - 239821281879927

The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

Bradley AR. et al, (2017), Essays in Biochemistry, 61, 495 - 503

Maximising value from a United Kingdom Biomedical Research Centre: study protocol.

Greenhalgh T. et al, (2017), Health Res Policy Syst, 15

Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors

Lines KE. et al, (2017), Oncogenesis, 6, e332 - e332

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.

Tumber A. et al, (2017), Cell Chem Biol, 24, 371 - 380

Establishing a reliable framework for harnessing the creative power of the scientific crowd.

Carter AJ. et al, (2017), PLoS Biol, 15

Assessing histone demethylase inhibitors in cells: lessons learned.

Hatch SB. et al, (2017), Epigenetics Chromatin, 10

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