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Preclinical drug studies in MEN1-related neuroendocrine neoplasms (MEN1-NENs).

Journal article

Grozinsky-Glasberg S. et al, (2020), Endocrine-related cancer, 27, R345 - R355

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells

Journal article

Lines KE. et al, (2020), Endocrine-Related Cancer, 27, 163 - 174

Organizational Innovation for Developing New Medicines That Target Aging and Age-Related Conditions.

Journal article

Ford GA. et al, (2020), The journals of gerontology. Series A, Biological sciences and medical sciences, 75, 87 - 88

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function

Journal article

Fagan V. et al, (2019), Journal of Medicinal Chemistry, 62, 9008 - 9025

A genetics-led approach defines the drug target landscape of 30 immune-related traits

Journal article

Fang H. et al, (2019), Nature Genetics, 51, 1082 - 1091

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

Journal article

D'Ascenzio M. et al, (2019), Angewandte Chemie International Edition, 58, 1007 - 1012

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors

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Vazquez‐Rodriguez S. et al, (2019), Angewandte Chemie International Edition, 58, 515 - 519

Donated chemical probes for open science

Journal article

Müller S. et al, (2018), eLife, 7

Therapeutics discovery: From bench to first in-human trials*

Journal article

Al-Hujaily E. et al, (2018), Biomedical Reports

Open innovation in neuroscience research and drug discovery

Journal article

Hunter AJ. et al, (2018), Brain and Neuroscience Advances, 2, 239821281879927 - 239821281879927

Assessing histone demethylase inhibitors in cells: lessons learned

Journal article

Hatch SB. et al, (2017), Epigenetics & Chromatin, 10

Maximising value from a United Kingdom Biomedical Research Centre: study protocol

Journal article

Greenhalgh T. et al, (2017), Health Research Policy and Systems, 15

Establishing a reliable framework for harnessing the creative power of the scientific crowd

Journal article

Carter AJ. et al, (2017), PLOS Biology, 15, e2001387 - e2001387

Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1

Journal article

Zhang C. et al, (2016), Biochemical Pharmacology, 117, 35 - 45

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