Hypoxic microenvironment shapes HIV-1 replication and latency
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Zhuang X. et al, (2020), Communications Biology, 3
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI.
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Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression.
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Orlando IMC. et al, (2019), Haematologica
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
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Schmid V. et al, (2019), Scientific Reports, 9
MITF controls the TCA cycle to modulate the melanoma hypoxia response.
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Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma.
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Purshouse K. et al, (2019), BMC cancer, 19
Inherent DNA ‐binding specificities of the HIF ‐1α and HIF ‐2α transcription factors in chromatin
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Smythies JA. et al, (2019), EMBO reports, 20
Studying the effects of disease associated polymorphism on a transcriptional pathway: A case study in renal cell carcinoma
Conference paper
Schmid V. et al, (2018), EUROPEAN JOURNAL OF HUMAN GENETICS, 26, 549 - 550
Studying effects of disease associated polymorphism on a transcriptional pathway: A case study in renal cell cancer
Conference paper
Schmid V. and Mole D., (2018), CANCER RESEARCH, 78
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
Journal article
Tiana M. et al, (2018), Nucleic Acids Research, 46, 120 - 133
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
Journal article
Tiana M. et al, (2017)
Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway
Journal article
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Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer
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Grampp S. et al, (2016), Nature Communications, 7
Capture‐C reveals preformed chromatin interactions between HIF ‐binding sites and distant promoters
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Platt JL. et al, (2016), EMBO reports, 17, 1410 - 1421
Clinical features of the pathogenic m.5540G>A mitochondrial transfer RNA tryptophan gene mutation
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Ng YS. et al, (2016), Neuromuscular Disorders, 26, 702 - 705
Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel–Lindau Gene Mutation Status
Journal article
Messai Y. et al, (2016), European Urology, 70, 623 - 632
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
Journal article
Chan MC. et al, (2016), Journal of Biological Chemistry, 291, 20661 - 20673
Hypoxic regulation of the noncoding genome and NEAT1
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Choudhry H. and Mole DR., (2016), Briefings in Functional Genomics, 15, 174 - 185
Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer
Journal article
Schödel J. et al, (2016), European Urology, 69, 646 - 657
Abstract A29: Hypoxia regulated long noncoding RNAs and antisense transcripts in breast cancer: Novel insights of noncoding transcriptional regulation in hypoxic microenvironment
Conference paper
Choudhry H. et al, (2016), Regulation of Noncoding RNAs in Cancer