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Publications

Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI.

Lauer V. et al, (2020), The Journal of biological chemistry, 295, 4065 - 4078

Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression.

Orlando IMC. et al, (2019), Haematologica

Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer

Schmid V. et al, (2019), Scientific Reports, 9

MITF controls the TCA cycle to modulate the melanoma hypoxia response.

Louphrasitthiphol P. et al, (2019), Pigment cell & melanoma research, 32, 792 - 808

Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma.

Purshouse K. et al, (2019), BMC cancer, 19

Inherent DNA ‐binding specificities of the HIF ‐1α and HIF ‐2α transcription factors in chromatin

Smythies JA. et al, (2019), EMBO reports, 20

Studying the effects of disease associated polymorphism on a transcriptional pathway: A case study in renal cell carcinoma

Schmid V. et al, (2018), EUROPEAN JOURNAL OF HUMAN GENETICS, 26, 549 - 550

Studying effects of disease associated polymorphism on a transcriptional pathway: A case study in renal cell cancer

Schmid V. and Mole D., (2018), CANCER RESEARCH, 78

The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia

Tiana M. et al, (2018), Nucleic Acids Research, 46, 120 - 133

The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia

Tiana M. et al, (2017)

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway

Grampp S. et al, (2017), PLOS Genetics, 13, e1006872 - e1006872

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

Grampp S. et al, (2016), Nature Communications, 7

Capture‐C reveals preformed chromatin interactions between HIF ‐binding sites and distant promoters

Platt JL. et al, (2016), EMBO reports, 17, 1410 - 1421

Clinical features of the pathogenic m.5540G>A mitochondrial transfer RNA tryptophan gene mutation

Ng YS. et al, (2016), Neuromuscular Disorders, 26, 702 - 705

Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel–Lindau Gene Mutation Status

Messai Y. et al, (2016), European Urology, 70, 623 - 632

Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

Chan MC. et al, (2016), Journal of Biological Chemistry, 291, 20661 - 20673

Hypoxic regulation of the noncoding genome and NEAT1

Choudhry H. and Mole DR., (2016), Briefings in Functional Genomics, 15, 174 - 185

Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

Schödel J. et al, (2016), European Urology, 69, 646 - 657

Abstract A29: Hypoxia regulated long noncoding RNAs and antisense transcripts in breast cancer: Novel insights of noncoding transcriptional regulation in hypoxic microenvironment

Choudhry H. et al, (2016), Regulation of Noncoding RNAs in Cancer

Suppression of plasma hepcidin by venesection during steady-state hypoxia

Talbot NP. et al, (2016), Blood, 127, 1206 - 1207

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