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Publications

Just Another Flare of Ulcerative Colitis?

Kennedy J. et al, (2020), Gastroenterology, 158, e11 - e12

Extended Analysis Identifies Drug-Specific Association of Two Distinct HLA Class II Haplotypes for Development of Immunogenicity to Adalimumab and Infliximab.

Powell Doherty RD. et al, (2020), Gastroenterology

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease.

Serra EG. et al, (2020), Nature communications, 11

Autologous stem cell transplantation in refractory Crohn’s disease – low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study

Snowden JA. et al, (2019), BMC Gastroenterology, 19

The Inflammatory Bowel Disease Drug Azathioprine Induces Autophagy via mTORC1 and the Unfolded Protein Response Sensor PERK.

Hooper KM. et al, (2019), Inflammatory bowel diseases, 25, 1481 - 1496

The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy.

Biskou O. et al, (2019), PloS one, 14

Fecal microbiota profiles in treatment-naïve pediatric inflammatory bowel disease – associations with disease phenotype, treatment, and outcome

Olbjørn C. et al, (2019), Clinical and Experimental Gastroenterology, 12, 37 - 49

Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease

Klasić M. et al, (2018), Clinical Epigenetics, 10

The role of genetics in Crohn’s disease: how could it influence future therapies?

Geremia A. and Satsangi J., (2018), Expert Review of Gastroenterology & Hepatology, 12, 1075 - 1077

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury

Crittenden S. et al, (2018), Immunology and Cell Biology, 96, 1049 - 1059

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

Boyapati RK. et al, (2018), Inflammatory Bowel Diseases, 24, 2113 - 2122

Open: Lymphoma Risk and Overall Safety Profile of Adalimumab in Patients With Crohnʼs Disease With up to 6 Years of Follow-up in the PYRAMID Registry

DʼHaens G. et al, (2018), American Journal of Gastroenterology, 113, 872 - 882

Autologous Haematopoietic Stem Cell Transplantation for Crohn’s Disease: A Retrospective Survey of Long-term Outcomes From the European Society for Blood and Marrow Transplantation

Brierley CK. et al, (2018), Journal of Crohn's and Colitis

Top-down in the Long Term in Crohn’s Disease

Boyapati RK. et al, (2018), Journal of Crohn's and Colitis, 12, 513 - 514

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease

Baillie JK. et al, (2018), PLOS Computational Biology, 14, e1005934 - e1005934

Editorial: the influence of genetic factors in mediating the effects of tobacco smoke in IBD

Adams A. et al, (2018), Alimentary Pharmacology & Therapeutics, 47, 306 - 307

MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation

Ho G-T. et al, (2018), Mucosal Immunology, 11, 120 - 130

A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

Satsangi J. et al, (2017), Efficacy and Mechanism Evaluation, 4, 1 - 60

Fine-mapping inflammatory bowel disease loci to single-variant resolution

Huang H. et al, (2017), Nature, 547, 173 - 178

Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial

Lindsay JO. et al, (2017), The Lancet Gastroenterology & Hepatology, 2, 399 - 406

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