Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation
Journal article
Staller E. et al, (2024), Nature Communications, 15
Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II.
Journal article
Keown J. et al, (2024), Journal of virology
Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample
Journal article
Keown JR. et al, (2023), Nature Communications, 14
Protein target highlights in CASP15: Analysis of models by structure providers.
Journal article
Alexander LT. et al, (2023), Proteins
Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein
Journal article
Whitehead JD. et al, (2023), Acta Crystallographica Section F Structural Biology Communications, 79, 51 - 60
Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies
Journal article
Keown JR. et al, (2022), Nature Communications, 13
The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome
Journal article
Wang F. et al, (2022), Nucleic Acids Research, 50, 5713 - 5725
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification
Journal article
Baddock HT. et al, (2022), Nucleic Acids Research
The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a.
Journal article
Veler H. et al, (2022), Journal of virology
The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme
Journal article
Walker AP. et al, (2021), Nucleic Acids Research, 49, 13019 - 13030
Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins
Journal article
Renner M. et al, (2021), Nature Communications, 12
Structure of an H3N2 influenza virus nucleoprotein
Journal article
Knight ML. et al, (2021), Acta Crystallographica Section F Structural Biology Communications, 77, 208 - 214
Structural insights into RNA polymerases of negative-sense RNA viruses
Journal article
te Velthuis AJW. et al, (2021), Nature Reviews Microbiology, 19, 303 - 318
Diamond Light Source: contributions to SARS-CoV-2 biology and therapeutics
Journal article
Walsh MA. et al, (2021), Biochemical and Biophysical Research Communications, 538, 40 - 46
Host ANP32A mediates the assembly of the influenza virus replicase
Journal article
Carrique L. et al, (2020), Nature, 587, 638 - 643
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Journal article
Peng Y. et al, (2020), Nature Immunology, 21, 1336 - 1345
3D Correlative Cryo-Structured Illumination Fluorescence and Soft X-ray Microscopy Elucidates Reovirus Intracellular Release Pathway
Journal article
Kounatidis I. et al, (2020), Cell, 182, 515 - 530.e17
Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases
Journal article
Walker AP. et al, (2020)
High-resolution crystal structure of arthropod Eiger TNF suggests a mode of receptor engagement and altered surface charge within endosomes
Journal article
Bertinelli M. et al, (2019), Communications Biology, 2
The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins
Journal article
El Omari K. et al, (2019), Nature Communications, 10