Optimized protocol for CRISPR knockout of human iPSC-derived macrophages
Journal article
Navarro-Guerrero E. et al, (2024), STAR Protocols, 5, 102903 - 102903
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes.
Journal article
Antcliffe DB. et al, (2024), Thorax
Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study.
Journal article
Hägele P. et al, (2024), The Lancet. Haematology, 11, e114 - e126
Reframing sepsis immunobiology for translation: towards informative subtyping and targeted immunomodulatory therapies.
Journal article
Shankar-Hari M. et al, (2024), The Lancet. Respiratory medicine
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.
Journal article
Weeratunga P. et al, (2023), Nature communications, 14
Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance.
Journal article
Amarasinghe HE. et al, (2023), BMC genomics, 24
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.
Journal article
van Amstel RBE. et al, (2023), Intensive care medicine
A second update on mapping the human genetic architecture of COVID-19.
Journal article
COVID-19 Host Genetics Initiative None., (2023), Nature, 621, E7 - E26
A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.
Journal article
Akbari P. et al, (2023), Nature communications, 14
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
Journal article
Pairo-Castineira E. et al, (2023), Nature, 619, E61 - E61
Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination
Journal article
Yin Z. et al, (2023), Cell Reports, 42, 112470 - 112470
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Journal article
Pairo-Castineira E. et al, (2023), Nature, 617, 764 - 768
Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis.
Journal article
Kwok AJ. et al, (2023), Nat Immunol
Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
Journal article
Brown AC. et al, (2023), Cell Genomics, 100306 - 100306
Persistence of inflammatory and vascular mediators 5 months after hospitalization with COVID-19 infection
Journal article
Melhorn J. et al, (2023), Frontiers in Medicine, 10
Chromosome conformation capture approaches to investigate 3D genome architecture in Ankylosing Spondylitis
Journal article
Davidson C. et al, (2023), Frontiers in Genetics, 14
BurkHostGEN: a study protocol for evaluating variations in the Burkholderia pseudomallei and host genomes associated with melioidosis infection.
Journal article
Angchagun K. et al, (2023), Wellcome open research, 8
Erratum: Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial (American Journal of Respiratory and Critical Care Medicine (2019) 199 (980–986) DOI: 10.1164/rccm.201807-1419OC)
Journal article
Antcliffe DB. et al, (2022), American Journal of Respiratory and Critical Care Medicine, 206, 1572 - 1573
Association between age and the host response in critically ill patients with sepsis.
Journal article
Michels EHA. et al, (2022), Critical care (London, England), 26
Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity
Journal article
Gilchrist JJ. et al, (2022), Nature Communications, 13