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Regular RNA screening detects asymptomatic SARS-CoV-2 infection in haemodialysis patients.

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An ontogenetic switch drives the positive and negative selection of B cells

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High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

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Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

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An essential role for the Zn2+ transporter ZIP7 in B cell development

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Interventions for chronic kidney disease in people with sickle cell disease

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Themis2 lowers the threshold for B cell activation during positive selection

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Cheng D. et al, (2017), Nature Immunology, 18, 205 - 213

VEGF regulates local inhibitory complement proteins in the eye and kidney

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Keir LS. et al, (2016), Journal of Clinical Investigation, 127, 199 - 214

Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity

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Complex Genetic Control of Autoimmune Disease


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Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing

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Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

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B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8− dendritic cells require the intramembrane endopeptidase SPPL2A

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