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SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile
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CD56bright natural killer cells preferentially kill proliferating CD4+ T cells
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Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes
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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
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Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus
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Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases
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Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression
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Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice.
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A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease
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The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus
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The DILfrequency study is an adaptive trial to identify optimal IL-2 dosing in patients with type 1 diabetes
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