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Publications

Screening and Production of Recombinant Human Proteins: Protein Production in Insect Cells.

Mahajan P. et al, (2021), Methods in molecular biology (Clifton, N.J.), 2199, 67 - 94

Screening and Production of Recombinant Human Proteins: Protein Production in E. coli.

Burgess-Brown NA. et al, (2021), Methods in molecular biology (Clifton, N.J.), 2199, 45 - 66

Screening and Production of Recombinant Human Proteins: Ligation-Independent Cloning.

Strain-Damerell C. et al, (2021), Methods in molecular biology (Clifton, N.J.), 2199, 23 - 43

Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers.

Newman JA. et al, (2021), Life science alliance, 4

The SNM1A DNA repair nuclease.

Baddock HT. et al, (2020), DNA repair, 95

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.

Sieberts SK. et al, (2020), Scientific data, 7

RecQ helicases in DNA repair and cancer targets.

Newman JA. and Gileadi O., (2020), Essays in biochemistry, 64, 819 - 830

Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification

Baddock HT. et al, (2020)

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.

van der Lelij P. et al, (2020), Life science alliance, 3

SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.

Wells C. et al, (2020), ACS medicinal chemistry letters, 11, 340 - 345

The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity.

Newman JA. et al, (2020), The Journal of biological chemistry, 295, 2948 - 2958

Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors.

Profeta GS. et al, (2019), Scientific reports, 9

Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72.

Laflamme C. et al, (2019), eLife, 8

A Chemical Probe Targeting AAK1 and BMP2K

Wells C. et al, (2019)

Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2.

Serafim RAM. et al, (2019), ACS medicinal chemistry letters, 10, 1266 - 1271

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin

Lim M. et al, (2019), Structure, 27, 1316 - 1325.e6

Streamlining the production of proteins for structural biology

Owens RJ. and Gileadi O., (2019), Biophysical Reviews, 11, 533 - 534

Open laboratory notebooks: good for science, good for society, good for scientists

Schapira M. and Harding RJ., (2019), F1000Research, 8, 87 - 87

Role of protein structure in variant annotation: structural insight of mutations causing 6-pyruvoyl-tetrahydropterin synthase deficiency

Muniz JRC. et al, (2019), Pathology, 51, 274 - 280

The C-terminal domains SnRK2-box and ABA-box have a role in sugarcane SnRK2s auto-activation and activity

Righetto G. et al, (2019)

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