Chronic viral mimicry induction following p53 loss promotes immune evasion.
Ishak CA. et al, (2025), Cancer discovery
Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways.
Feng S. et al, (2024), Nature communications, 15
In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.
Su P. et al, (2024), Nature genetics
Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia
de Castro FA. et al, (2023), British Journal of Haematology
macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma.
Nikolic A. et al, (2023), Nature communications, 14
PRMT inhibition induces a viral mimicry response in triple-negative breast cancer.
Wu Q. et al, (2022), Nature chemical biology, 18, 821 - 830
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells
Loo Yau H. et al, (2021), Molecular Cell, 81, 1469 - 1483.e8
Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
Mehdipour P. et al, (2020), Nature, 588, 169 - 173
The role of DNA-demethylating agents in cancer therapy
Mehdipour P. et al, (2020), Pharmacology & Therapeutics, 205, 107416 - 107416