Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
Journal article
Du Y. et al, (2023), The Journal of biological chemistry
Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides
Journal article
O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609
The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system.
Journal article
Fazazi MR. et al, (2023), Brain research bulletin
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Journal article
Bashore FM. et al, (2023), bioRxiv
Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer's disease.
Journal article
Du Y. et al, (2023), bioRxiv
Open drug discovery in Alzheimer's disease.
Journal article
Axtman AD. et al, (2023), Alzheimer's & dementia (New York, N. Y.), 9
Development of Selective ADAMTS-5 Peptide Substrates to Monitor Proteinase Activity
Journal article
Fowkes MM. et al, (2023), Journal of Medicinal Chemistry
Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors
Journal article
Schuller M. et al, (2023), Pathogens, 12, 324 - 324
Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane.
Journal article
Frank N. et al, (2022), Nature
Covalent fragment-based ligand screening approaches for identification of novel ubiquitin proteasome system modulators
Journal article
Rothweiler EM. et al, (2022), Biological Chemistry, 403, 391 - 402
Imaging articular cartilage in osteoarthritis using targeted peptide radiocontrast agents.
Journal article
Fowkes MM. et al, (2022), PloS one, 17
Kalirin as a Novel Treatment Target for Cognitive Dysfunction in Schizophrenia
Journal article
Mould AW. et al, (2022), CNS Drugs, 36, 1 - 16
Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening.
Journal article
Mackinnon SR. et al, (2022), Frontiers in chemistry, 10
Target 2035-update on the quest for a probe for every protein
Journal article
Mueller S. et al, (2021), RSC MEDICINAL CHEMISTRY
A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation
Journal article
Nizami S. et al, (2021), Scientific Reports, 11
Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation
Journal article
Nizami S. et al, (2021), Scientific Reports, 11
The structural basis of fatty acid elongation by the ELOVL elongases
Journal article
Nie L. et al, (2021), Nature Structural & Molecular Biology, 28, 512 - 520
Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia
Journal article
Mackinnon SR. et al, (2021), ACS Chemical Biology, 16, 586 - 595
Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity.
Journal article
Doss PMIA. et al, (2021), Cell reports, 34
Chemogenomics for drug discovery: clinical molecules from open access chemical probes
Journal article
Quinlan RBA. and Brennan PE., (2021), RSC Chemical Biology, 2, 759 - 795