HIF2α: the interface between oxygen-sensing systems in physiology and pathology
Bishop T. and Ratcliffe PJ., (2025), Physiology
Conserved patterns of transcriptional dysregulation, heterogeneity, and cell states in clear cell kidney cancer.
Lombardi O. et al, (2025), Cell reports, 44
Hif-2α programmes oxygen chemosensitivity in chromaffin cells
Prange-Barczynska M. et al, (2024), Journal of Clinical Investigation
N-terminal cysteine acetylation and oxidation patterns may define protein stability
Heathcote KC. et al, (2024), Nature Communications, 15
Oncogenic cell tagging and single-cell transcriptomics reveal cell type-specific and time-resolved responses to Vhl inactivation in the kidney
Kurlekar S. et al, (2024), Cancer Research
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Ma J. et al, (2024), Proceedings of the National Academy of Sciences of the United States of America, 121
Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells
Tian Y-M. et al, (2023), Journal of Biological Chemistry, 105156 - 105156
Pan-Cancer Analysis of Tissue and Single-Cell HIF-Pathway Activation Using a Conserved Gene Signature
Lombardi O. et al, (2023), SSRN Electronic Journal
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma
Lafleur VN. et al, (2023), Life Science Alliance, 6, e202201756 - e202201756
Author Correction: Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation.
Mirchandani AS. et al, (2022), Nature immunology, 23
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6
Cockman ME. et al, (2022), Proceedings of the National Academy of Sciences, 119
Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins.
Leissing TM. et al, (2022), The Journal of biological chemistry, 298
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation.
Mirchandani AS. et al, (2022), Nature immunology, 23, 927 - 939
Publisher Correction: Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation.
Frise MC. et al, (2022), Scientific reports, 12
Harveian Oration 2020: Elucidation of molecular oxygen sensing mechanisms in human cells: implications for medicine.
Ratcliffe PJ., (2022), Clinical medicine (London, England), 22, 23 - 33
Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma.
Eckardt L. et al, (2021), Endocrine-related cancer, 28, 757 - 772
Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia
Jatho A. et al, (2021), Circulation Research, 128, 1208 - 1210
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
Wing PAC. et al, (2021), Cell Reports, 35, 109020 - 109020
Hypoxic and Pharmacological Activation of HIF Inhibits SARS-CoV-2 Infection of Lung Epithelial Cells
Wing PAC. et al, (2020), SSRN Electronic Journal
Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center.
Aitken J. et al, (2020), Nature biotechnology, 38