DNA polymerase ε produces elevated C-to-T mutations at methylated CpG dinucleotides.
(2024), Nature genetics, 56, 2304 - 2305
Human DNA polymerase ε is a source of C>T mutations at CpG dinucleotides
Tomkova M. et al, (2024), Nature Genetics, 56, 2506 - 2516
Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome
Xu H. et al, (2024), Nature Methods
Modular Oxidation of Cytosine Modifications and Their Application in Direct and Quantitative Sequencing of 5-Hydroxymethylcytosine.
Xu H. et al, (2023), Journal of the American Chemical Society, 145, 7095 - 7100
A critique of the hypothesis that CA repeats are primary targets of neuronal MeCP2.
Chhatbar K. et al, (2022), Life science alliance, 5
Decitabine increases neoantigen and cancer testis antigen expression to enhance T-cell-mediated toxicity against glioblastoma.
Ma R. et al, (2022), Neuro-oncology, 24, 2093 - 2106
LKB1 cooperates with Sox17 to drive metastasis.
Kriaucionis S., (2021), Nature cell biology, 23, 816 - 817
Endonuclease enrichment TAPS for cost-effective genome-wide base-resolution DNA methylation detection.
Cheng J. et al, (2021), Nucleic acids research, 49
Neuronal non-CG methylation is an essential target for MeCP2 function.
Tillotson R. et al, (2021), Mol Cell
Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors
Cusack M. et al, (2020), Genome Research, 30, 1393 - 1406
ATACing DNA Methylation during Differentiation.
Kriaucionis S. and Klose RJ., (2020), Molecular cell, 77, 1159 - 1161
The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression.
Thomas R. et al, (2019), Scientific reports, 9
Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads
Müller CA. et al, (2019), Nature Methods, 16, 429 - 436
From herbal small RNAs to one medicine
Ji C. et al, (2019), Science China Life Sciences, 62, 285 - 287
The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.
Gdula MR. et al, (2019), Nat Commun, 10
Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein
Motnenko A. et al, (2018), PLOS Genetics, 14, e1007643 - e1007643
Mutational signature distribution varies with DNA replication timing and strand asymmetry.
Tomkova M. et al, (2018), Genome Biol, 19