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Publications

BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination

Becker JR. et al, (2021), Nature

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Hewitt G. et al, (2021), Molecular Cell, 81, 767 - 783.e11

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

Yeow ZY. et al, (2020), Nature, 585, 447 - 452

Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining.

Francica P. et al, (2020), Cell reports, 32

BARD1 links histone H2A Lysine-15 ubiquitination to initiation of BRCA1-dependent homologous recombination

Becker JR. et al, (2020)

An essential role for the Zn2+ transporter ZIP7 in B cell development

Anzilotti C. et al, (2019), Nature Immunology, 20, 350 - 361

H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids

Nakamura K. et al, (2019), Nature Cell Biology, 21, 311 - 318

H4K20meO recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids

Nakamura K. et al, (2019), NATURE CELL BIOLOGY, 21, 311 - +

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity

Becker JR. et al, (2018), Nature Communications, 9

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ

Ghezraoui H. et al, (2018), Nature, 560, 122 - 127

Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein

Botuyan MV. et al, (2018), Nature Structural & Molecular Biology, 25, 591 - 600

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

Barazas M. et al, (2018), Cell Rep, 23, 2107 - 2118

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

Altemose N. et al, (2017), eLife, 6

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

Altemose N. et al, (2017), ELIFE, 6

Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility.

Wright DJ. et al, (2017), Nat Genet, 49, 674 - 679

A 53BP1 integrates DNA repair and p53-dependent cell fate decisions via distinct mechanisms

Cuella-Martin R. et al, (2017), MOLECULAR CANCER RESEARCH, 15

53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms.

Cuella-Martin R. et al, (2016), Mol Cell, 64, 51 - 64

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Day FR. et al, (2015), Nat Genet, 47, 1294 - 1303

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

Xu G. et al, (2015), Nature, 521, 541 - 544

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

Chapman JR. et al, (2013), Mol Cell, 49, 858 - 871

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