Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Continue

Publications

BARD1 links histone H2A Lysine-15 ubiquitination to initiation of BRCA1-dependent homologous recombination

Becker JR. et al, (2020)

An essential role for the Zn2+ transporter ZIP7 in B cell development

Anzilotti C. et al, (2019), Nature Immunology, 20, 350 - 361

H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids

Nakamura K. et al, (2019), Nature Cell Biology, 21, 311 - 318

H4K20meO recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids

Nakamura K. et al, (2019), NATURE CELL BIOLOGY, 21, 311 - +

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity.

Becker JR. et al, (2018), Nat Commun, 9

53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.

Ghezraoui H. et al, (2018), Nature, 560, 122 - 127

Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.

Botuyan MV. et al, (2018), Nat Struct Mol Biol, 25, 591 - 600

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

Barazas M. et al, (2018), Cell Rep, 23, 2107 - 2118

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

Altemose N. et al, (2017), eLife, 6

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

Altemose N. et al, (2017), ELIFE, 6

Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility.

Wright DJ. et al, (2017), Nat Genet, 49, 674 - 679

A 53BP1 integrates DNA repair and p53-dependent cell fate decisions via distinct mechanisms

Cuella-Martin R. et al, (2017), MOLECULAR CANCER RESEARCH, 15

53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms.

Cuella-Martin R. et al, (2016), Mol Cell, 64, 51 - 64

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Day FR. et al, (2015), Nat Genet, 47, 1294 - 1303

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

Xu G. et al, (2015), Nature, 521, 541 - 544

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

Chapman JR. et al, (2013), Mol Cell, 49, 858 - 871

Playing the end game: DNA double-strand break repair pathway choice.

Chapman JR. et al, (2012), Mol Cell, 47, 497 - 510

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.

Chapman JR. et al, (2012), J Cell Sci, 125, 3529 - 3534

Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.

Polo SE. et al, (2012), Mol Cell, 45, 505 - 516

The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis.

Taylor EM. et al, (2010), Nucleic Acids Res, 38, 441 - 454

Load More

Include forthcoming?