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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.

Journal article

Leach JDG. et al, (2021), Nature communications, 12

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

Journal article

Flanagan DJ. et al, (2021), Nature

BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration.

Journal article

Koppens MA. et al, (2021), Gastroenterology

Advances in colon cancer research: in vitro and animal models

Journal article

Lannagan TR. et al, (2021), Current Opinion in Genetics and Development, 66, 50 - 56

Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer.

Conference paper

Nowinski S. et al, (2020), CANCER RESEARCH, 80

Stromal imbalance of bone morphogenetic protein signaling drives colorectal carcinogenesis

Conference paper

Kobayashi H. et al, (2020), JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 35, 160 - 160

A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

Journal article

Demetriou P. et al, (2020), Nature Immunology, 21, 1232 - 1243

Gremlin 1 - small protein, big impact: the multiorgan consequences of disrupted BMP antagonism†.

Journal article

Gooding S. and Leedham SJ., (2020), The Journal of pathology, 251, 349 - 352

Reserving the Right to Change the Intestinal Stem Cell Model

Journal article

Leedham SJ., (2020), Cell Stem Cell, 26, 301 - 302

Intestine, Heal Thyself! Regulating the Intestinal Epithelial Response to Injury.

Journal article

Leedham SJ., (2020), Cellular and molecular gastroenterology and hepatology

Remission of Inflammatory Bowel Disease in Glucose-6-Phosphatase 3 Deficiency by Allogeneic Haematopoietic Stem Cell Transplantation

Journal article

Bolton C. et al, (2020), Journal of Crohn's and Colitis, 14, 142 - 147

Deciphering the molecular signalling underpinning early-dissemination and metastasis from stage I colorectal cancer

Conference paper

Dunne P. et al, (2019), BRITISH JOURNAL OF CANCER, 121, 4 - 4

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