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Publications

A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

Demetriou P. et al, (2020), Nature Immunology, 21, 1232 - 1243

Gremlin 1 - small protein, big impact: the multiorgan consequences of disrupted BMP antagonism†.

Gooding S. and Leedham SJ., (2020), The Journal of pathology, 251, 349 - 352

GENERATION OF A GASTRIC ADENOCARCINOMA AND PROXIMAL POLYPOSIS OF THE STOMACH (GAPPS) MOUSE THAT PHENOCOPIES HUMAN DISEASE

Suzuki N. et al, (2020), GASTROENTEROLOGY, 158, S160 - S160

Reserving the Right to Change the Intestinal Stem Cell Model

Leedham SJ., (2020), Cell Stem Cell, 26, 301 - 302

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease.

Serra EG. et al, (2020), Nature communications, 11

Intestine, Heal Thyself! Regulating the Intestinal Epithelial Response to Injury.

Leedham SJ., (2020), Cellular and molecular gastroenterology and hepatology

Remission of Inflammatory Bowel Disease in Glucose-6-Phosphatase 3 Deficiency by Allogeneic Haematopoietic Stem Cell Transplantation

Bolton C. et al, (2020), Journal of Crohn's and Colitis, 14, 142 - 147

Deciphering the molecular signalling underpinning early-dissemination and metastasis from stage I colorectal cancer

Dunne P. et al, (2019), BRITISH JOURNAL OF CANCER, 121, 4 - 4

Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification

Kleeman SO. et al, (2019), Gut

The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression.

Thomas R. et al, (2019), Scientific reports, 9

A Quantitative Evolutionary Approach Utilising High Resolution Chromosomal Copy Number Analysis Accurately Stratifies Patients with Ulcerative Colitis and Low Grade Dysplasia by Future Colorectal Cancer Risk

Al Bakir I. et al, (2019), JOURNAL OF PATHOLOGY, 249, S12 - S12

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions

Leng T. et al, (2019), Cell Reports, 28, 3077 - 3091.e5

Evolutionary history of human colitis-associated colorectal cancer

Baker A-M. et al, (2019), Gut, 68, 985 - 995

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Law PJ. et al, (2019), Nature communications, 10

Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis

Lannagan TRM. et al, (2019), Gut, 68, 684 - 692

The evolutionary landscape of colorectal tumorigenesis

Cross W. et al, (2018), Nature Ecology & Evolution, 2, 1661 - 1672

Advancing the molecular understanding of stage I colorectal cancer

Dunne P. et al, (2018), CANCER RESEARCH, 78

The evolutionary history of human colitis-associated colorectal cancer

Baker A-M. et al, (2018), CANCER RESEARCH, 78

Correction: Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel

Fernandez-Rozadilla C. et al, (2018), British Journal of Cancer, 118, 1683 - 1683

SHALLOW WHOLE-GENOME SEQUENCING PREDICTS THE FUTURE CANCER RISK OF LOW-GRADE DYSPLASTIC LESIONS IN ULCERATIVE COLITIS

Al Bakir I. et al, (2018), GUT, 67, A53 - A54

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