Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
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Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences
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Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma.
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Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
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Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
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Silent hypoxaemia in COVID‐19 patients
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Hypoxic and Pharmacological Activation of HIF Inhibits SARS-CoV-2 Infection of Lung Epithelial Cells
Wing PAC. et al, (2020), SSRN Electronic Journal
Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control
Cheng X. et al, (2020), Journal of Clinical Investigation, 130, 2237 - 2251
Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4
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Systemic silencing of Phd2 causes reversible immune regulatory dysfunction
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PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies
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Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2
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Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice
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Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
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Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
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HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
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Augmented 5-HT Secretion in Pulmonary Neuroepithelial Bodies from PHD1 Null Mice
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Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives
Peter Ratcliffe P. and Bishop T., (2014), Hypoxia, 197 - 197
Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 allele and null for prolyl hydroxylase domain protein 1 (Men1+/-/Phd1-/-)
Stevenson M. et al, (2014), Endocrine Abstracts
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
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