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Publications

Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.

Chen S. et al, (2020), Cancer cell

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution

Louphrasitthiphol P. et al, (2020), Molecular Cell

Correction: Motion sensing superpixels (MOSES) is a systematic computational framework to quantify and discover cellular motion phenotypes.

Zhou FY. et al, (2019), Elife, 8

Altered DNA modifications in Barrett's oesophagus and oesophageal adenocarcinoma

Kriaucionis S. et al, (2019), CANCER RESEARCH, 79

Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy.

O'Donnell-Luria AH. et al, (2019), Am J Hum Genet

Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells.

Wang Y. et al, (2019), Autophagy, 15, 886 - 899

Motion sensing superpixels (MOSES) is a systematic computational framework to quantify and discover cellular motion phenotypes.

Zhou FY. et al, (2019), Elife, 8

Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands

Owen RP. et al, (2018), Nature Communications, 9

Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively.

Wang Y. et al, (2018), J Cell Sci, 131

Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.

Ryzhakov G. et al, (2018), Nat Commun, 9

Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders.

Dedeić Z. et al, (2018), Cell Death Differ, 25, 1289 - 1303

BEARscc determines robustness of single-cell clusters using simulated technical replicates.

Severson DT. et al, (2018), Nat Commun, 9

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.

Papaspyropoulos A. et al, (2018), Nat Commun, 9

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.

Yeh T-L. et al, (2017), Chem Sci, 8, 7651 - 7668

Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.

Falletta P. et al, (2017), Genes Dev, 31, 18 - 33

ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome.

Zak J. et al, (2016), Cell Death Differ, 23, 1973 - 1984

Structure-function relationships of human JmjC oxygenases-demethylases versus hydroxylases.

Markolovic S. et al, (2016), Curr Opin Struct Biol, 41, 62 - 72

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

Lu M. et al, (2016), Cancer Cell, 30, 822 - 823

p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration.

Turnquist C. et al, (2016), Cell Death Differ, 23, 1515 - 1528

Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding.

Lu M. et al, (2016), Nat Rev Mol Cell Biol, 17, 523 - 532

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