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Publications

STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming.

Chu Z. et al, (2022), Nature communications, 13

Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis.

Xu W. et al, (2022), Mol Cell

Author Correction: LSD1 inhibition sustains T cell invigoration with a durable response to PD-1 blockade.

Liu Y. et al, (2022), Nature communications, 13

LSD1 inhibition sustains T cell invigoration with a durable response to PD-1 blockade.

Liu Y. et al, (2021), Nature communications, 12

Chromatin-state barriers enforce an irreversible mammalian cell fate decision

Blanco MA. et al, (2021), Cell Reports, 37, 109967 - 109967

Simultaneous Inhibition of LSD1 and TGFβ Enables Eradication of Poorly Immunogenic Tumors with Anti-PD-1 Treatment.

Sheng W. et al, (2021), Cancer discovery, 11, 1970 - 1981

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia.

Zee BM. et al, (2021), iScience, 24

The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.

Stielow B. et al, (2021), Science advances, 7

Nucleotide resolution profiling of m3C RNA modification by HAC-seq

Cui J. et al, (2021), Nucleic Acids Research, 49, e27 - e27

METTL3 regulates heterochromatin in mouse embryonic stem cells.

Xu W. et al, (2021), Nature, 591, 317 - 321

meCLICK-Seq, a Substrate-Hijacking and RNA Degradation Strategy for the Study of RNA Methylation.

Mikutis S. et al, (2020), ACS central science, 6, 2196 - 2208

METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing

Chen H. et al, (2020), Cell Research, 30, 544 - 547

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

Anastas JN. et al, (2019), Cancer Cell, 36, 528 - 544.e10

PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression

Sendinc E. et al, (2019), Molecular Cell, 75, 620 - 630.e9

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

Sheng W. et al, (2018), Cell, 174, 549 - 563.e19

Polycomb-like proteins link the PRC2 complex to CpG islands

Li H. et al, (2017), Nature, 549, 287 - 291

RNA m6A methylation regulates the ultraviolet-induced DNA damage response

Xiang Y. et al, (2017), Nature, 543, 573 - 576

Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex

Shen H. et al, (2016), Cell, 165, 331 - 342

A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation.

Iwase S. et al, (2016), Cell reports, 14, 1000 - 1009

DNA Methylation on N6-Adenine in C. elegans

Greer EL. et al, (2015), Cell, 161, 868 - 878

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