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Calman A. MacLennan

BM, BCh, DPhil, FRCP, FRCPath

Professor of Vaccine Immunology (University of Birmingham)

  • MRC Senior Clinical Fellow, Jenner Investigator and Group Leader - Gonococcal Vaccine Project, Jenner Institute
  • Senior Program Officer - Bacterial Vaccines; Lead - Shigella Portfolio & Salmonella Vaccines Product Development, Global Health - Enteric & Diarrheal Diseases, Bill & Melinda Gates Foundation
  • Director, BactiVac Bacterial Vaccinology Network; Professor of Vaccine Immunology, University of Birmingham
  • Consultant Immunologist, Oxford University Hospitals NHS Trust

My main research objective is to understand the immunological basis of protection against invasive bacterial disease with a view to prevention and treatment, focusing on communities in resource-limited settings and patients with impaired immunity. My programme at the Jenner Institute aims to combine improved understanding of naturally-acquired immunity and vaccine-induced immunity to invasive bacteria, focusing on Salmonella, with a view to the development of effective and affordable vaccines against these pathogens for use in the developing world. This work involves partnership and collaboration with sites in low-income countries and exploitation of effective and affordable vaccine technologies, such as Generalized Modules for Membrane Antigens (GMMA).