Dr Claire M Keene
Contact information
Research groups
Colleges
Claire Keene
MBBCh, MSc, PhD
Researcher and Deputy Director of the MSc HSIE
- Deputy Director, MSc in Health Service Improvement and Evaluation
- Health systems and epidemiology researcher
Current Research
My research focuses on examining engagement of people on antiretroviral therapy with HIV care in South Africa. Understanding how people engage with health services and their treatment over time is crucial to adapting service structure to respond to the changing needs of people in care. I am currently a co-investigator on a study trialing a novel model of care for people with a recent history of disengagement, in order to support better long-term engagement in Gugulethu, South Africa (SUStained HIV Treatment Adherence After Interruption; SUSTAIN2). This could help to direct the development of resource-efficient, differentiated services for people not coping with current services. I am also interested in applying precision public health principles to explore the applications of routine data in stratifying the people on antiretroviral treatment for more targeted intervention.
Education
DPhil in Clinical Medicine University of Oxford, Nuffield Department of Clinical Medicine. St John's College (United Kingdom). 2020-2024
Thesis: Exploring engagement with antiretroviral care for people living with HIV in a high burden setting in South Africa
MSc in International Health and Tropical Medicine (with distinction) University of Oxford, Nuffield Department of Clinical Medicine. Lincoln College (United Kingdom). 2016-2017
Thesis: Competing-risk approach to modelling length of stay in severe malaria patients in South-East Asia and the implications for planning of hospital services.
Diplomas in
- Public Health: Faculty of Public Health (United Kingdom). 2022
- Tropical Medicine and Hygiene: Royal College of Physicians (United Kingdom). 2017
- HIV Management: The Colleges of Medicine of South Africa (South Africa). 2016
MBBCh (with distinction) University of the Witwatersrand, Health Sciences Faculty (South Africa). 2007-2012
Previous Experience
Co-principal investigator then co-investigator for the AntiRetroviral Therapy In Second-line: investigating Tenofovir-lamivudine-dolutegravir (ARTIST) trial. Khayelitsha, South Africa. 2018 to present.
HIV medical activities manager, then project medical referent (medical coordinator) for Médecins Sans Frontières Khayelitsha, South Africa. 2018 to 2020
Research assistant for the Oxford Health Systems Collaborative, University of Oxford. 2017 to 2018
Medical doctor for the South African Department of Health. 2013-2016.
Founder and co-owner of Study Doctor Tutoring. 2009-2019
Recent publications
ntiretroviral Therapy Adherence Interventions in the Era of Universal Test and Treat: A Hybrid Systematic-Narrative Literature Review of Global Evidence
Journal article
Keene CM. et al, (2026), AIDS and Behavior, 30, 291 - 306
Longitudinal patterns of antiretroviral treatment interruptions in a high burden, low-resource setting in South Africa: a retrospective cohort study
Journal article
Keene CM. et al, (2025), The Lancet Primary Care, 1, 100077 - 100077
Reducing HIV incidence and mortality: two sides of the same coin in the approach to ending AIDS.
Journal article
Jarvis JN. et al, (2025), The lancet. HIV
Retention in a low-resource, high-burden South African cohort on antiretroviral therapy: Retrospective, longitudinal analysis comparing six measures of retention.
Journal article
Keene CM. et al, (2025), Journal of the International AIDS Society, 28
Oral antiretroviral adherence interventions in the era of U=U
Journal article
Keene CM. et al, (2025), The Lancet HIV, 12, e587 - e595