Postdoctoral Research Scientist - Protein and Antibody Production
I obtained my PhD in Biochemistry and Molecular Biology at the Autonomous University of Barcelona. During my early research years I studied the innate immune system as a source of novel antibiotics, using the antimicrobial structural determinants of the human ribonucleases to develop new therapeutic agents.
After my PhD I moved to Imperial College London as a Postdoctoral Scientist in Professor Hohenester's Laboratory, where I expanded my knowledge and skills in protein production, structural biology and biophysics, especially in X-ray crystallography.
After my first postdoctoral experience I moved to the Structural Genomics Consortium, University of Oxford, where I consolidated myself as a structural biologist and protein production expert, developing novel drugs against autophagy regulators.
Currently, I am a Senior Postdoctoral Scientist working in Professor Simon J Draper's laboratory at the Jenner Institute, University of Oxford. My work is focused in the identification of improved antigen targets within the blood-stage merozoite malaria parasite; and the development and production of structure-guided protein based vaccines according to GMP standards.
Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies
Alanine DGW. et al, (2019), Cell, 178, 216 - 228.e21
Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1
Pulido D. et al, (2018), Structure, 26, 1384 - 1392.e3
Positional scanning library applied to the human eosinophil cationic protein/RNase3 N-terminus reveals novel and potent anti-biofilm peptides
Pulido D. et al, (2018), European Journal of Medicinal Chemistry, 152, 590 - 599
Structural similarities in the CPC clip motif explain peptide-binding promiscuity between glycosaminoglycans and lipopolysaccharides
Pulido D. et al, (2017), Journal of The Royal Society Interface, 14, 20170423 - 20170423
Host Antimicrobial Peptides: The Promise of New Treatment Strategies against Tuberculosis
Arranz-Trullén J. et al, (2017), Frontiers in Immunology, 8