George Busby
Contact information
George Busby
Post-doctoral research associate
Research overview
George works in Chris Spencer's group in Oxford as a collaboration with MalariaGEN on the analysis of human genetic data. He explores the effects of demography and natural selection on the human genome. He is currently working with a large African dataset developing new models to identify regions of the genome that may have been altered in response to infectious disease. He is also interested in using genetic data to uncover novel inferences about our evolutionary past, and has helped developed models that characterise recent human admixture history.
Selected publications
Montinaro F, Busby, GBJ, Pascali VL, Myers S, Hellenthal G, Capelli C Unravelling the hidden ancestry of american admixed populations. (in press) Nature Communications.
Hellenthal G, Busby, GBJ, Band G, Wilson JF, Capelli C, Falush D, Myers S (2014) A genetic atlas of human admixture history. Science 343: 747–751
Busby, GBJ, Brisighelli F, Sánchez-Diz P, Ramos-Luis E, Martinez-Cadenas C, Thomas MG, Bradley DG, GusmãoL, Winney B, Bodmer W, Vennemann M, Coia V, Scarnicci F, Tofanelli S, Vona G, Ploski R, Vecchiotti C, Zemunik T, Rudan I, Karachanak S, Toncheva D, Anagnostou P, Ferri G, Rapone C, Hervig T, Moen T, Wilson JF, Capelli C (2012) The peopling of Europe and the cautionary tale of y chromosome lineage r-m269. Proceedings of the Royal Society B: Biological Sciences 279: 884 –892.
Recent publications
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Integrating a Polygenic Risk Score for Coronary Artery Disease as a Risk-Enhancing Factor in the Pooled Cohort Equation: A Cost-Effectiveness Analysis Study.
Journal article
Mujwara D. et al, (2022), J Am Heart Assoc, 11
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Risk of Coronary Artery Disease Conferred by Low-Density Lipoprotein Cholesterol Depends on Polygenic Background.
Journal article
Bolli A. et al, (2021), Circulation, 143, 1452 - 1454
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Detection of B.1.351 SARS-CoV-2 Variant Strain - Zambia, December 2020.
Journal article
Mwenda M. et al, (2021), MMWR. Morbidity and mortality weekly report, 70, 280 - 282
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Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania.
Journal article
Malaria Genomic Epidemiology Network None., (2019), Nature communications, 10
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Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
Journal article
Ndila CM. et al, (2018), The Lancet Haematology, 5, e333 - e345