Colleges
Ian Tomlinson
Professor of Molecular and Population Genetics
- The identification of genes that predispose to colorectal and other cancers
- Functional genetics of colorectal tumorigenesis, with emphasis on the relative importance of selection and genomic instability.
- Cancer genes and metabolism.
- Cancer evolution.
Recent publications
Characterisation of bacteria‐induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease
Journal article
Hart DW. et al, (2026), The Journal of Pathology, 268, 493 - 511
HLA Heterozygosity Influences Colorectal Cancer Risk and Survival Outcome.
Journal article
Tsai Y-Y. et al, (2026), Gastroenterology, 170, 619 - 622
Negative Selection Maintains Grossly Altered but Broadly Stable Karyotypes in Metastatic Colorectal Cancer.
Journal article
Cross WCH. et al, (2026), Cancer discovery, 16, 218 - 234
Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer.
Journal article
Billaud A. et al, (2026), Breast (Edinburgh, Scotland), 85
Promises under pressure: the modest predictive power of polygenic risk scores
Journal article
Horton R. et al, (2026), European Journal of Human Genetics