Colleges
Ian Tomlinson
Professor of Molecular and Population Genetics
- The identification of genes that predispose to colorectal and other cancers
- Functional genetics of colorectal tumorigenesis, with emphasis on the relative importance of selection and genomic instability.
- Cancer genes and metabolism.
- Cancer evolution.
Recent publications
Characterisation of bacteria‐induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease
Journal article
Hart DW. et al, (2026), The Journal of Pathology
Promises under pressure: the modest predictive power of polygenic risk scores
Journal article
Horton R. et al, (2026), European Journal of Human Genetics
HLA Heterozygosity Influences Colorectal Cancer Risk and Survival Outcome.
Journal article
Tsai Y-Y. et al, (2026), Gastroenterology
Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility.
Journal article
Chen Z. et al, (2026), Nature communications
Negative Selection Maintains Grossly Altered but Broadly Stable Karyotypes in Metastatic Colorectal Cancer.
Journal article
Cross WCH. et al, (2026), Cancer discovery, OF1 - OF17