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Peter Donelly

Contact information

Email
donnelly@well.ox.ac.uk

Website
The Wellcome Centre for Human Genetics

Podcast: Human Genetics

Colleges

St Anne's College

Peter Donnelly

FRS FMedSci

Professor of Statistical Science

We are interested in understanding the impact of recombination in shaping natural diversity and evolution. We are also interested in understanding the mechanisms promoting and regulating recombination in mammals.

The Donnelly group, in collaboration with others, has developed and applied cutting-edge statistical methods that utilize genome-wide variation data to detect and characterise human population structure and admixture.

Recent publications

Preventing premature deaths through polygenic risk scores.

Chuong M. et al, (2026), Nature communications, 17

Polygenic risk score adds to a clinical risk score in the prediction of cardiovascular disease in a clinical setting.

Samani NJ. et al, (2024), European heart journal, 45, 3152 - 3160

A polygenic risk score added to a QRISK®2 cardiovascular disease risk calculator demonstrated robust clinical acceptance and clinical utility in the primary care setting.

Fuat A. et al, (2024), European journal of preventive cardiology, 31, 716 - 722

Meiotic DNA breaks drive multifaceted mutagenesis in the human germ line.

Hinch R. et al, (2023), Science (New York, N.Y.), 382

Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice

Davies B. et al, (2023), Genome Research, 33, 2018 - 2027

More publications