Colleges
Peter Donnelly
FRS FMedSci
Professor of Statistical Science
We are interested in understanding the impact of recombination in shaping natural diversity and evolution. We are also interested in understanding the mechanisms promoting and regulating recombination in mammals.
The Donnelly group, in collaboration with others, has developed and applied cutting-edge statistical methods that utilize genome-wide variation data to detect and characterise human population structure and admixture.
Recent publications
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Meiotic DNA breaks drive multifaceted mutagenesis in the human germ line.
Hinch R. et al, (2023), Science (New York, N.Y.), 382
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Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice
Davies B. et al, (2023), Genome Research, 33, 2018 - 2027
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2022 William Allan Award.
Donnelly P., (2023), American journal of human genetics, 110, 404 - 408
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Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary
Davies B. et al, (2021), Molecular Biology and Evolution, 38, 5555 - 5562
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Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries.
Weale ME. et al, (2021), The American journal of cardiology, 148, 157 - 164