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Contact information


ricardo.fernandes@ndm.ox.ac.uk

Receptor Inhibition by Phosphatase Recruitment

Research groups

Ricardo A. Fernandes

CAMS Oxford Institute Group Leader

Cancer Immunology - T cell signalling

The main objective of our research group is to identify key functional aspects affecting anti-tumor responses by T cells. To do this, we use protein engineering, guided by structural and signaling information, to generate novel molecules that allow us to explore and interrogate key aspects of receptor signaling and T cell function. We are currently focusing our efforts in developing molecules to overcome “inhibitory” signaling by immune checkpoint receptors and to enhance signaling by the T-cell receptor.     

Ricardo Fernandes recently joined CAMS Oxford Institute coming from Stanford where he developed novel molecules to effectively shut down signaling by immune receptors such as PD-1.  

Recent publications

More publications