Research groups
Colleges
Rob Beagrie
Group Leader / Sir Henry Dale Fellow
- Group Leader at the Wellcome Centre for Human Genetics
- Sir Henry Dale Fellow
Rob joined the Wellcome Centre for Human Genetics as a new Group Leader in April 2022, supported by a Wellcome Sir Henry Dale Fellowship. Rob heads the Chromatin and Disease group, which uses experimental and computational approaches to study human genetic diseases caused by chromatin dysfunction.
Rob studied Biochemistry at Cambridge University, then did his doctoral research with Prof. Ana Pombo at Imperial College and the Max Delbruck Centre in Berlin. Rob was then awarded a Sir Henry Wellcome Postdoctoral Fellowship to move to the MRC Weatherall Institute of Molecular Medicine and work with Prof. Doug Higgs on gene expression in early red blood cell differentiation.
Key publications
Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C
Journal article
Beagrie RA. et al, (2023), Nature Methods, 20, 1037 - 1047
GAMtools: an automated pipeline for analysis of Genome Architecture Mapping data
Preprint
Beagrie RA. and Schueler M., (2017)
Recent publications
FACT safeguards promoter topology by maintaining nucleosomes and restricting chromatin factor spreading
Preprint
Dopico-Fernandez AM. et al, (2026)
ncient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis
Journal article
Preston AE. et al, (2025), Nature Communications, 16