Thuy Le
Dr
My research interest is in reducing disease burden, improving diagnostics and treatment of HIV-associated infections through epidemiology, laboratory technologies and clinical trials. My major disease areas of interest are HIV-associated opportunistic infections, specifically Penicillium marneffei infection, HIV drug resistance, and HIV-HCV coinfection. I collaborate closely with major hospitals providing HIV care throughout Vietnam. Currently I am the Principal Investigator of 2 ongoing multi-center clinical trials, one comparing amphotericin B and itraconazole in the treatment of HIV-associated penicilliosis, the other to evaluate the safety of raltegravir compared to efavirenz in HIV-HCV coinfection. I also lead and collaborate on studies to understand disease epidemiology, identifying risk factors for infections, and improving diagnostics and treatment of penicilliosis.
Recent publications
Clinical features of three patients with paradoxical immune reconstitution inflammatory syndrome associated with Talaromyces marneffei infection
Journal article
Thanh NT. et al, (2018), Medical Mycology Case Reports, 19, 33 - 37
Fungal infections in HIV/AIDS
Journal article
Limper AH. et al, (2017), The Lancet Infectious Diseases, 17, e334 - e343
Itraconazole and antiretroviral therapy: strategies for empirical dosing – Author's reply
Other
Le T. et al, (2017), The Lancet Infectious Diseases, 17, 1123 - 1124
Itraconazole or Amphotericin B for Talaromycosis
Journal article
(2017), New England Journal of Medicine, 377, 1402 - 1403
Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis
Journal article
Le T. et al, (2017), New England Journal of Medicine, 376, 2329 - 2340