The department supports investigator-led research through a series of well-founded laboratories. This research covers every aspect of biological science related to medicine: from the bench to the bedside, from blue sky to full clinical trials, from technology development to spin-out. It covers many fields and many clinical disciplines.
The department supports this research in an environment designed to foster the long-term career development of fellows and research staff.
All of the above is made possible through the generosity and long-term support of our sponsors and funders.
A study led by Professor Xin Lu has linked the gene for ASPP2, a regulator of p53, to a rare genetic disorder - 1q41q42 microdeletion syndrome, characterised by dysmorphic features, intellectual disability and brain morphological abnormalities
Scientists from the UK and USA have used the intense X-rays generated at Diamond Light Source to gain important insights into how target molecules in skin cancer treatment can become resistant to drugs designed to fight the cancer, leading to ineffective treatment. “We are extremely excited by our results because the Smoothened molecule is a very unusual protein and it was technically very challenging to determine its crystal structure", explains Prof Christian Siebold.