The department supports investigator-led research through a series of well-founded laboratories. This research covers every aspect of biological science related to medicine: from the bench to the bedside, from blue sky to full clinical trials, from technology development to spin-out. It covers many fields and many clinical disciplines.
The department supports this research in an environment designed to foster the long-term career development of fellows and research staff.
All of the above is made possible through the generosity and long-term support of our sponsors and funders.
A group of prominent scientists, including Daniel Ebner from the TDI, shared their opinion in Nature Reviews Drug Discovery about ineffective academic and industrial drug discovery investments and funding structures. Parallel competitive research and development funding restricted to traditional drug discovery operating models is suggested as one major contributing factor to the exponential increase in the cost of new medicines.
There has been considerable interest about the extent to which genetic factors interact with environmental and lifestyle factors in human traits. Alex Young and colleagues in Peter Donnelly’s group at the Wellcome Trust Centre for Human Genetics have used the latest UK Biobank data to discover novel interactions between genetic variants at the FTO locus and lifestyle factors, including sleep duration and alcohol consumption.