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Professor Sarah Gilbert awarded RSA Albert Medal

News

NDM's Professor Sarah Gilbert has been awarded the Royal Society for Arts’ (RSA) Albert Medal for her work on the Oxford vaccine. Professor Gilbert is Professor of Vaccinology and the Oxford Project Leader for ChAdOx1 nCoV-19, a vaccine against the novel coronavirus, SARSCoV-2, with approval for use in many countries around the world.

World’s largest clinical trial for COVID-19 treatments expands internationally

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The Randomised Evaluation of COVID-19 Therapy (RECOVERY) Trial, the world’s largest clinical trial for COVID-19 treatments, has now expanded internationally with Indonesia and Nepal among the first countries to join and recruited to RECOVERY International. NDM's Peter Horby, Professor of Emerging Infectious Diseases and Global Health, and Joint Chief Investigator for the trial, said ‘The RECOVERY trial has been an enormous success, enrolling over 36,000 patients and delivering clear results on six treatments already. By building on this success through international partnership we can speed up the assessment of novel treatments, increase the global relevance of the trial results, build capacity, and reduce wasted efforts on small uninformative studies".

Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer’s disease

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Exscientia, the leading AI Drug Discovery company, has today announced its collaboration with the Alzheimer’s Research UK Oxford Drug Discovery Institute (ARUK-ODDI) to develop medicines targeting neuroinflammation for the treatment of Alzheimer’s disease (AD).

Tocilizumab reduces deaths in patients hospitalised with COVID-19

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The Randomised Evaluation of COVID-19 Therapy (RECOVERY) has demonstrated that an anti-inflammatory treatment, tocilizumab, reduces the risk of death when given to hospitalised patients with severe COVID-19.

Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests

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Early treatment with a medication commonly used to treat asthma appears to significantly reduce the need for urgent care and hospitalisation in people with COVID-19, researchers at the University of Oxford have found.

Oxford Cancer Centre appoints Professor Tim Elliot as new co-director

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The CRUK Oxford Centre is pleased to announce the appointment of Professor Tim Elliot as its new co-Director. Tim has recently joined the Nuffield Department of Medicine and Oriel College as the Kidani Professor of Immuno-Oncology. He re-joins the Oxford community from Southampton University, having previously completed his undergraduate degree in Biochemistry at Balliol and subsequently holding a Professorial post at the Weatherall Institute for Molecular Medicine.

Lateral flow devices detect most infectious COVID-19 cases and could allow a safer relaxation of the current lockdown

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Researchers from NDM's Big Data Institute working with Public Health England and NHS Test and Trace, have used Test and Trace data to find out why some individuals pass COVID-19 on to their contacts more easily than others, and if lateral flow tests are sufficient in detecting those who are most infectious

National consortium to study threats of new SARS-CoV-2 variants

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A new national research project to study the effects of emerging mutations in SARS-CoV-2 will be launched with £2.5 million funding from UK Research and Innovation (UKRI).

Professor Sir Dave Stuart, FRS FMedSci knighted in New Year's Honours

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Congratulations to Sir Dave Stuart, FRS FMedSci, NDM’s Professor of Structural Biology, knighted for services to medical research and the scientific community.

Oxford University welcomes UK regulatory emergency use authorisation of coronavirus vaccine

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The Nuffield Department of Medicine welcomes the news that the UK Government has today accepted the recommendation from the Medicines and Healthcare products Regulatory Agency (MHRA) to authorise the emergency use of the ChAdOx1 nCoV-19 coronavirus vaccine in the UK.

Professor Susie Dunachie awarded flagship NIHR career development award

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Susie Dunachie joins a prestigious group of leading health researchers in the latest cohort of NIHR Global Research Professors. These awards fund research leaders of the future to promote effective translation of research and to strengthen health, public health and care research leadership at the highest academic levels. Research conducted by Global Research Professors directly benefits people in LMICs. A Consultant in Infectious Diseases and Medical Microbiology, Susie works on the development of a vaccine to prevent death from melioidosis in people with type 2 diabetes mellitus in LMICs, and supports vaccine research in Thailand.

RECOVERY trial finds no benefit from azithromycin in patients hospitalised with COVID-19

News

RECOVERY reports absence of a benefit from Azithromycin. The latest result from the NDM/NDPH RECOVERY trial shows the widely administered administration of a broad-spectrum antibiotic makes no difference to the routine outcome in hospitalised COVID19 disease. Results on other therapies are likely to follow in the coming weeks.

National COVID-19 Infections Survey reveals changes to pandemic over time

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Data from the National COVID-19 Infection Survey, done in partnership between the University of Oxford, the Office of National Statistics, Public Health England, University of Manchester and the Wellcome Trust, has revealed detailed characteristics of England’s coronavirus pandemic, including which factors have contributed most to case numbers over different phases and the prevalence of asymptomatic infections.

First peer-reviewed results of phase 3 human trials of Oxford coronavirus vaccine demonstrate efficacy

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Today, the University of Oxford and AstraZeneca researchers present a pooled analysis of Phase 3 trials of a vaccine against SARS-CoV-2 across two different dose regimens, resulting in an average efficacy of 70.4%. The new study published in the Lancet is the first peer-reviewed publication of phase 3 data from studies of a vaccine against the coronavirus.

Oxford University breakthrough on global COVID-19 vaccine

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The University of Oxford, in collaboration with AstraZeneca plc, today announces interim trial data from its Phase III trials that show its candidate vaccine, ChAdOx1 nCoV-2019, is effective at preventing COVID-19 (SARS-CoV-2) and offers a high level of protection.

Oxfordshire Young Scientists of the Year 2020

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This year's Young Scientists of the Year 2020 events for outstanding Year 13 science students in Oxfordshire and Buckinghamshire took place on Wednesday 19 November together with their families and teachers attending via zoom!

Oxford ramps up COVID-19 testing capability

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The University of Oxford has joined forces with Thermo Fisher Scientific, the world leader in serving science, to ramp up the university’s capacity to deliver COVID-19 testing data.

Trials of Oxford coronavirus vaccine begin in Kenya

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Kenya has joined the global efforts in search of an effective vaccine for COVID-19 with the start of a trial evaluating the ChAdOx1 nCoV-2019 Oxford coronavirus vaccine. Following the necessary approvals from regulators, as well as the national ministry of health, and Kilifi county, the first volunteers for the trial have recently received their vaccinations.

NDM New Professors

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The University's latest Recognition of Distinction Exercise has awarded the Nuffield Department of Medicine three new Professors; Elisabeth Ashley - Professor of Tropical Medicine. Stuart Blacksell - Professor of Tropical Microbiology and John B Davis - Professor of Pharmaceutical Discovery.

NDM’s Jenner Institute appoints first Bvlgari Scholars

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Following the announcement in June of a new philanthropic relationship between Bvlgari and the University of Oxford, Bvlgari’s donation in support of DPhil students in vaccine research benefits two exceptional students, appointed as the first cohort of Bvlgari Scholars. The Jenner Institute welcomes students Cameron Bissett and Rebecca Makinson this month for the start of their DPhil courses, after demonstrating remarkable academic potential and merit in the field of vaccine-related immunology.

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