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A highly drug resistant malaria "superbug" from western Cambodia is now present in southern Vietnam, leading to alarming failure rates for dihydroartemisinin (DHA)-piperaquine - Vietnam’s national first-line malaria treatment, leading malaria scientists warn.

Transnational spread of multidrug resistant PfPallin (Cambodia)The spread of this dominant artemisinin drug resistant t P falciparum C580Y mutant malaria parasite lineage across the entire Mekong Sub-region is a serious threat to malaria control and eradication efforts, the scientists say in a letter published today in The Lancet Infectious Diseases.

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Rift Valley fever vaccine to enter Phase II clinical trials in Kenya

A promising human vaccine candidate against the potentially deadly Rift Valley fever, a mosquito-borne disease affecting countries across Africa, is set to begin Phase II trials in Kenya. This is the most advanced stage of testing a human Rift Valley fever vaccine has reached in an outbreak-prone area to date. A team of scientists at the Nuffield Department of Medicine and the KEMRI-Wellcome Trust Research Programme will lead the $3.7m trial, funded by the Coalition for Epidemic Preparedness Innovations (CEPI).