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Researchers have reported the results of the first randomised clinical trial to test a novel strategy. The approach involves waking up and then killing the ‘sleeping’ HIV that is hiding in the body using an experimental approach known as ‘kick and kill’.

Led by Imperial College London, the University of OxfordMRC Clinical Trials Unit at UCL, and the University of Cambridge, the RIVER study aimed to improve on current care by eradicating HIV from the body, which would represent a major step forward in the search for a cure

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