Professor Jeremy Day
Contact information
Podcast interview
Central nervous system and HIV infections in Vietnam

Brain infections such as meningitis and encephalitis are highly debilitating diseases, and an accurate diagnostic is essential to give patients the best treatment available. For cryptococcal meningitis, clinical trials focus on prevention, for an early diagnosis, and novel ways to use existing treatments or repurpose old drugs.
Research groups
Jeremy Day
Professor of Infectious Diseases
CNS and HIV Infections
In the CNS-HIV infections research group we run a programme of science driven by randomized controlled trials powered to relevant and easily understandable clinical endpoints. The main areas of interest are opportunistic infections including cryptococcosis and penicilliosis, TB meningitis, acute bacterial meningitis, encephalitis and HIV drug resistance. In addition to improving patient outcomes, we are interested in innovative approaches to clinical trial design, health economics, ecology, epidemiology and determinants of pathogenicity of the organisms we study.
Recent publications
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Comparative Effectiveness of Regimens for Drug-Susceptible Tuberculous Meningitis in Children and Adolescents: A Systematic Review and Aggregate-Level Data Meta-Analysis.
Journal article
Sulis G. et al, (2022), Open forum infectious diseases, 9
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Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis
Preprint
Horby PW. et al, (2022)
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Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Journal article
Abani O. et al, (2022), The Lancet, 399, 143 - 151
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Antifungal Susceptibility Does Not Correlate With Fungal Clearance or Survival in AIDS-Associated Cryptococcal Meningitis.
Journal article
O'Connor L. et al, (2021), Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 73, e2338 - e2341
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An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis.
Journal article
Ngan NTT. et al, (2021), eLife, 10
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Adjunctive treatments for the management of septic shock – a narrative review of the current evidence
Journal article
Donovan K. et al, (2021), Anaesthesia, 76, 1245 - 1258
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Cryptococcal meningoencephalitis: time for action.
Journal article
Stott KE. et al, (2021), The Lancet. Infectious diseases, 21, e259 - e271