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Search results (125)

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Protein Target Highlights in CASP16 : Insights From the Structure Providers

Alexander LT. et al, (2026), Proteins: Structure, Function, and Bioinformatics, 94, 25 - 50

The E3 ubiquitin ligase MGRN1 targets melanocortin receptors MC1R and MC4R via interactions with transmembrane adapters.

Parashara P. et al, (2025), Journal of cell science, 138

Docking for Smoothened antagonist chemotypes not susceptible to a vismodegib-resistance mutation.

Titulaer WHC. et al, (2025), European journal of medicinal chemistry, 296

“Design principles of a membrane-spanning ubiquitin ligase”

Williams C. et al, (2025)

The E3 ubiquitin ligase MGRN1 targets melanocortin receptors MC1R and MC4R via interactions with transmembrane adapters.

Parashara P. et al, (2025), bioRxiv

Mapping structural and dynamic divergence across the MBOAT family.

Ansell TB. et al, (2024), Structure (London, England : 1993), 32, 1011 - 1022.e3

Molecular mechanism of BMP signal control by Twisted gastrulation

Malinauskas T. et al, (2024), Nature Communications, 15

Diverse genetic causes of amenorrhea in an ethnically homogeneous cohort and an evolving approach to diagnosis.

Bakhshalizadeh S. et al, (2024), Molecular and cellular endocrinology, 587

Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling.

Griffiths SC. et al, (2024), eLife, 13

Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase

Ritzefeld M. et al, (2024), Journal of Medicinal Chemistry, 67, 1061 - 1078

LipIDens: simulation assisted interpretation of lipid densities in cryo-EM structures of membrane proteins

Ansell TB. et al, (2023), Nature Communications, 14

Implementation of the LipIDens pipeline: assisted interpretation of lipid densities in membrane protein structures using simulations

Ansell TB. et al, (2023)

The energetics and ion coupling of cholesterol transport through Patched1

Ansell TB. et al, (2023), Science Advances, 9

The Inseparable Relationship Between Cholesterol and Hedgehog Signaling.

Siebold C. and Rohatgi R., (2023), Annual review of biochemistry, 92, 273 - 298

Rocking the MBOAT: Structural insights into the membrane bound O-acyltransferase family.

Coupland CE. et al, (2023), Current opinion in structural biology, 80

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