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The Nuffield Department of Medicine (NDM) at the University of Oxford has a global reach and significant breadth in terms of capabilities and capacity.
François Nosten: Between research and humanitarian
Combining healthcare and research allow Professor Nosten to implement a new treatment regimen as soon as the results from clinical trials are available, which is beneficial to patients and highly rewarding for researchers.
Arjen Dondorp: The treatment of severe malaria
Successful malaria control has meant a drop in mortality rates worldwide but it is still an important disease. Therapies using artesunate, a derivative of artemisinin drugs, aim to kill malaria parasites before they mature. These therapies have high success rates and need to be developed. General care of malaria patients also needs to be improved.
Nick White: Artemisinin therapy for malaria
Malaria is the most important parasitic disease of man. Although most of the deaths occur in Africa, drug resistance has emerged from South-East Asia. Artemisinins, which are plant-derived compounds originally from the Chinese Materia Medica, are still today the best treatment for malaria, however, other drugs are also showing promising results. Clinical trials are also undertaken to find out the correct doses. All these developments contribute to our progress in getting malaria under control.