BA (Cantab), MA (Cantab), D.Phil. (Oxon)
Associate Professor, Research Informatics
- Chair of NDORMS IT/Comms/Informatics Committee
After completing a D.Phil. within the Iain Campbell lab at the University of Oxford, Brian was awarded a Wellcome Trust Prize Fellowship which he spent at the Abagyan lab at the Scripps Research Institute, La Jolla, USA, devising novel methods for proteins structure superimposition and also implementing high performance compute and storage clusters. He then worked as part of the Computational Chemistry group at BioFocus PLC before settling down at the SGC in Oxford and now the Centre for Medicines Discovery where he continues to be responsible for all aspects of Informatics, IT and structural bioinformatics. He has a particular interest in the development of novel data capture and visualisation methods for structural and chemical biology data.
Since 2013, Brian has split his time with the Kennedy Institute where he and his team are responsible for the provision of IT capabilities as well as effective data management platforms to support the broad range of science within the Institute.
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Thompson KN. et al, (2023), Science translational medicine, 15
Protection against SARS-CoV-2 Omicron BA.4/5 variant following booster vaccination or breakthrough infection in the UK.
Wei J. et al, (2023), Nature communications, 14
Improving the representativeness of UK’s national COVID-19 Infection Survey through spatio-temporal regression and post-stratification
Pouwels KB. et al, (2023)
Correlates of protection against SARS-CoV-2 Omicron variant and anti-spike antibody responses after a third/booster vaccination or breakthrough infection in the UK general population
Wei J. et al, (2022)
Pathogenic Interleukin-10 Receptor Alpha Variants in Humans — Balancing Natural Selection and Clinical Implications
Aschenbrenner D. et al, (2022), Journal of Clinical Immunology