BA (Cantab), MA (Cantab), D.Phil. (Oxon)
Associate Professor, Research Informatics
- Chair of NDORMS IT/Comms/Informatics Committee
After completing a D.Phil. within the Iain Campbell lab at the University of Oxford, Brian was awarded a Wellcome Trust Prize Fellowship which he spent at the Abagyan lab at the Scripps Research Institute, La Jolla, USA, devising novel methods for proteins structure superimposition and also implementing high performance compute and storage clusters. He then worked as part of the Computational Chemistry group at BioFocus PLC before settling down at the SGC in Oxford and now the Centre for Medicines Discovery where he continues to be responsible for all aspects of Informatics, IT and structural bioinformatics. He has a particular interest in the development of novel data capture and visualisation methods for structural and chemical biology data.
Since 2013, Brian has split his time with the Kennedy Institute where he and his team are responsible for the provision of IT capabilities as well as effective data management platforms to support the broad range of science within the Institute.
An Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status
Lumley SF. et al, (2022), Clinical Infectious Diseases, 74, 1208 - 1219
Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines
Wei J. et al, (2022), Nature Medicine
Fragment Hotspot Mapping to Identify Selectivity-Determining Regions between Related Proteins.
Smilova MD. et al, (2022), Journal of chemical information and modeling, 62, 284 - 294
Target 2035-update on the quest for a probe for every protein
Mueller S. et al, (2021), RSC MEDICINAL CHEMISTRY
Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections
Eyre DW. et al, (2021), BMC Infectious Diseases, 21