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CMD Research Informatics
Small Research Facility (SRF) providing bespoke data management and informatics solutions
Brian Marsden
BA (Cantab), MA (Cantab), D.Phil. (Oxon)
Professor of Practice in Data Management & Research Informatics
- Director of the NDM Data Platform
- Associate Head, Medical Sciences Division (Digital & Information)
- Chair, University Research Computing Subcommittee
- Member of Information and Digital Committee (IDC) and Research Portfolio Committee
- Chair of NIHR BRC Informatics Forum
Brian is responsible for driving research informatics and research computing capabilities at NDM and in particular the Centre for Human Genetics and the Centre for Medicines Discovery.
After completing a D.Phil. within the Iain Campbell lab at the University of Oxford, Brian was awarded a Wellcome Trust Prize Fellowship which he spent at the Abagyan lab at the Scripps Research Institute, La Jolla, USA, devising novel methods for proteins structure superimposition and also implementing high performance compute and storage clusters. He then worked as part of the Computational Chemistry group at BioFocus PLC before settling down at the SGC in Oxford and now the Centre for Medicines Discovery where he continues to be responsible for all aspects of Informatics, IT and structural bioinformatics. He has a particular interest in the development of novel data capture and visualisation methods for structural and chemical biology data.
Since 2023, Brian has been the Director of the NDM Biomedical Data Platform where he and his team are responsible for the provision of effective data management platforms to support the broad range of science within the department.
Recent publications
Expanding the genotypic spectrum of combined oxidative phosphorylation deficiency 54.
Journal article
Lai KL. et al, (2026), Neurogenetics, 27
The cumulative incidence and infection hospitalization risk of SARS-CoV-2 by variant: a longitudinal study in England
Journal article
Gaughan C. et al, (2026), American Journal of Epidemiology, 195, 188 - 197
Early lymph node T follicular helper cell signalling hub drives influenza vaccine response in an ancestrally diverse cohort
Journal article
Siu JHY. et al, (2025), eBioMedicine, 122, 106036 - 106036
Interpolation-Based Conditioning of Flow Matching Models for Bioisosteric Ligand Design
Preprint
Ziv Y. et al, (2025)
CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue.
Journal article
Liu F. et al, (2025), Annals of the rheumatic diseases, 84, 1151 - 1163