Chris O'Callaghan

Professor of Medicine, Honorary Consultant Physician and Nephrologist, Fellow of The Queen's College

The immune system plays a major role in many human diseases, including cancer, infection, atherosclerosis and autoimmune disease. A better understanding of the immune system should accelerate the design of better treatments for these diseases.

We study the function of the molecules and pathways involved in the immune response and the role of the immune system and inflammation in disease. The group employs a wide range of approaches to understand basic biology and disease mechanisms.

Recent publications

Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data
Journal article

Schlackow I. et al, (2020), PLOS Medicine, 17, e1003478 - e1003478
Hierarchical Modular DNA Assembly Using MetClo.
Journal article

Lin D. and O'Callaghan CA., (2020), Methods in molecular biology (Clifton, N.J.), 2205, 143 - 159
Effects of antihypertensives, lipid-modifying drugs, glycaemic control drugs and sodium bicarbonate on the progression of stages 3 and 4 chronic kidney disease in adults: a systematic review and meta-analysis.
Journal article

Taylor KS. et al, (2019), BMJ Open, 9
Statistical models for the deterioration of kidney function in a primary care population: A retrospective database analysis
Journal article

Oke JL. et al, (2019), F1000Research, 8, 1618 - 1618
Trends in kidney function testing in UK primary care since the introduction of the quality and outcomes framework: a retrospective cohort study using CPRD (vol 9, e028062, 2019)
Journal article

Feakins B. et al, (2019), BMJ OPEN, 9

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