Chris O'Callaghan
Contact information
Nuffield Department of Medicine
Henry Wellcome Building for Molecular Physiology
Colleges
Chris O'Callaghan
Professor of Medicine, Honorary Consultant Physician and Nephrologist, Fellow of The Queen's College
The immune system plays a major role in many human diseases, including cancer, infection, atherosclerosis and autoimmune disease. A better understanding of the immune system should accelerate the design of better treatments for these diseases.
We study the function of the molecules and pathways involved in the immune response and the role of the immune system and inflammation in disease. The group employs a wide range of approaches to understand basic biology and disease mechanisms.
Recent publications
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Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data
Journal article
Schlackow I. et al, (2020), PLOS Medicine, 17, e1003478 - e1003478
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Hierarchical Modular DNA Assembly Using MetClo.
Journal article
Lin D. and O'Callaghan CA., (2020), Methods in molecular biology (Clifton, N.J.), 2205, 143 - 159
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Effects of antihypertensives, lipid-modifying drugs, glycaemic control drugs and sodium bicarbonate on the progression of stages 3 and 4 chronic kidney disease in adults: a systematic review and meta-analysis.
Journal article
Taylor KS. et al, (2019), BMJ Open, 9
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Statistical models for the deterioration of kidney function in a primary care population: A retrospective database analysis
Journal article
Oke JL. et al, (2019), F1000Research, 8, 1618 - 1618
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Trends in kidney function testing in UK primary care since the introduction of the quality and outcomes framework: a retrospective cohort study using CPRD (vol 9, e028062, 2019)
Journal article
Feakins B. et al, (2019), BMJ OPEN, 9