Saleta Vazquez Rodriguez
Contact information
Research groups
Saleta Vazquez Rodriguez
Dr
Postdoctoral Researcher
Saleta Vazquez Rodriguez graduated in 2007 in Chemistry at the University of Santiago de Compostela (Spain). She did her final project at the Northern Institute for Cancer Research and at the University of Newcastle Upon Tyne (UK) under the supervision of Prof. Ian Hardcastle, Bernard Golding and Roger Griffin, where she worked in the development of inhibitors for p53-MDM2 interactions.
In 2010 she got an MSc in Organic Chemistry and in 2014 she obtained her PhD in Medicinal Chemistry under the supervision of Prof. Eugenio Uriarte and Prof. Lourdes Santana. Her research field during her PhD was focused on the development of nature inspired oxacycles with pharmacological applications. During her PhD, she developed several stays at the University of Hawai’I at Manoa (USA) under the supervision of Prof. Marcus Tius, and at the University of Porto (Portugal) under the supervision of Fernanda Borges.
In 2014, she developed a postdoctoral research at the University of Porto (Portugal) where she worked on the synthesis of benzopyrone derivatives as antioxdant agents.
In November 2015, Dr. Vazquez Rodriguez joined Paul Brennan’s group at the Target Discovery Institute as a postdoctoral researcher to work on the discovery of new chemical probes for lysine demethylase (KDM) inhibitors as novel epigenetic chemical probes.
Recent publications
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Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists
Journal article
Matos MJ. et al, (2020), Journal of Medicinal Chemistry, 63, 2577 - 2587
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Epigenetic Drug Discovery. Edited by Wolfgang Sippl and Manfred Jung
Journal article
Vazquez‐Rodriguez S., (2020), ChemMedChem, 15, 174 - 175
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Design, Synthesis and Characterization of Covalent KDM5 Inhibitors
Journal article
Vazquez‐Rodriguez S. et al, (2019), Angewandte Chemie International Edition, 58, 515 - 519
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Design, Synthesis and Characterization of Covalent KDM5 Inhibitors
Working paper
Vazquez-Rodriguez S. et al, (2018)
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Development of 8-pyridopyrimidinone-based covalent inhibitors of KDM5B
Conference paper
Wright M. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256