Thomas Crellen
I'm a postgraduate researcher working in the Bacterial Resistance Analysis Group in the Mahidol-Oxford Tropical Medicine Research Unit in Bangkok, Thailand. My project focusses on determining risk factors for acquisition of drug resistant bacteria among neonates in a Cambodian hospital. The main organism in both carriage and blood stream infections was Klebsiella pneumoniae, we have sequenced over 300 isolates and aim to use the whole genome data to reconstruct transmission networks within the ward.
Prior to starting at MORU I worked as a field epidemiologist for Médecins Sans Frontières in the Central African Republic and the Democratic Republic of Congo.
My PhD was at Imperial College London and the Wellcome Trust Sanger Institute, focussing on the genomics and epidemiology of Schistosoma mansoni, a neglected tropical disease.
Recent publications
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How useful is Nanopore adaptive sampling for sequencing Schistosoma mansoni miracidia?
Journal article
Lim RM. et al, (2025), Wellcome Open Research, 10, 239 - 239
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The genome sequence of the liver fluke Opisthorchis viverrini (Poirier, 1886) Stiles & Hassall, 1896
Journal article
Wangwiwatsin A. et al, (2025), Wellcome Open Research, 10, 1 - 1
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Natural history of a parasite-induced biliary cancer
Preprint
Crellen T. et al, (2024)
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Diagnostic value of urinary and serum IgG antibodies in evaluating drug treatment response in strongyloidiasis assessed by fecal examination and digital droplet PCR.
Journal article
Wongphutorn P. et al, (2024), PloS one, 19
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Modelling morbidity for neglected tropical diseases: the long and winding road from cumulative exposure to long-term pathology
Journal article
Borlase A. et al, (2023), Philosophical Transactions of the Royal Society B: Biological Sciences, 378