Thomas Crellen
I'm a postgraduate researcher working in the Bacterial Resistance Analysis Group in the Mahidol-Oxford Tropical Medicine Research Unit in Bangkok, Thailand. My project focusses on determining risk factors for acquisition of drug resistant bacteria among neonates in a Cambodian hospital. The main organism in both carriage and blood stream infections was Klebsiella pneumoniae, we have sequenced over 300 isolates and aim to use the whole genome data to reconstruct transmission networks within the ward.
Prior to starting at MORU I worked as a field epidemiologist for Médecins Sans Frontières in the Central African Republic and the Democratic Republic of Congo.
My PhD was at Imperial College London and the Wellcome Trust Sanger Institute, focussing on the genomics and epidemiology of Schistosoma mansoni, a neglected tropical disease.
Recent publications
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Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence
Journal article
Davis EL. et al, (2021), Nature Communications, 12
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Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration
Journal article
Berger DJ. et al, (2021), Nature Communications, 12
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Dynamics of SARS-CoV-2 with waning immunity in the UK population
Journal article
Crellen T. et al, (2021), Philosophical Transactions of the Royal Society B: Biological Sciences, 376
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Engagement and adherence trade-offs for SARS-CoV-2 contact tracing
Journal article
Lucas TCD. et al, (2021), Philosophical Transactions of the Royal Society B: Biological Sciences, 376
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Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients
Journal article
León-Sampedro R. et al, (2021), Nature Microbiology, 6, 606 - 616