The latest news, updates and announcements from the Nuffield Department of Medicine.
Aerosol human infection model gives hope for TB vaccine development
16 April 2024
University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body.
Chinese ambassador visits CAMS Oxford Institute
15 April 2024
The Chinese Ambassador to the United Kingdom, His Excellency Zheng Zeguang, visited the University of Oxford last week, where he promoted deeper educational exchanges between China and the UK. During the visit, Zheng met with Irene Tracey, Vice-Chancellor of the university, and had an in-depth discussion on the university’s collaboration with Chinese counterparts.
Novel biomarker’s accuracy for predicting preterm births confirmed
11 April 2024
A recent study by the Oxford University Clinical Research Unit and collaborators has validated a novel biomarker that accurately predicts preterm births. The research published in the Journal of Maternal-Fetal & Neonatal Medicine represents an important advancement in the early detection and management of preterm labour risks, with potential implications for improving maternal and neonatal health outcomes in the Southeast Asian region.
Rapid diagnostic test offers cost-effective solutions for non-malarial febrile illness
10 April 2024
New research by the Mahidol Oxford Tropical Medicine Research Unit, explores the potential benefits of a presumptive lateral flow rapid diagnostic test in managing acute non-malarial febrile illness (NMFI) patient care in rural areas of Southeast Asia.
Francesco Boccellato receives Lee Placito Research Fellowship
8 April 2024
Dr Francesco Boccellato, Leadership Fellow at the Oxford Branch of the Ludwig Institute for Cancer Research has recently been awarded the Lee Placito Research Fellowship in Gastrointestinal Cancer.
Oxford hosts Belgian vaccine experts
5 April 2024
Researchers from Oxford Vaccine Group and the Pandemic Sciences Institute welcomed a delegation of vaccine researchers from Belgium to further UK-Belgian collaboration on vaccine development and manufacture.
OUCRU celebrates World Health Worker Week 2024
4 April 2024
In the first week of April each year, the global community comes together to celebrate health workers, the backbone of the health industry and society.
Novel pairing of proteins controls tumour growth
3 April 2024
New research by the CAMS Oxford Institute, the MRC Translational Immune Discovery Unit and the Kennedy Institute researchers describes a novel pairing of integrins which could improve T cell control of cancer.
Early changes after a gene inactivation shape kidney cancer initiation
2 April 2024
A study from the Ratcliffe research group of NDM’s Ludwig Institute for Cancer Research has demonstrated the early events defining the cell-type specificity of the development of a tumour, providing a focus for mechanistic understanding and therapeutic targeting.
OUCRU researchers contribute to WHO’s diagnostic handbook on TB
28 March 2024
Members of the Oxford University Clinical Research Unit’s Tuberculosis group have contributed to the World Health Organization's latest edition of the tuberculosis (TB) diagnostic handbook. The "WHO operational handbook on tuberculosis" is an important resource for the rapid detection and diagnosis of tuberculosis (TB).
New rapid melioidosis test could save lives
27 March 2024
A new test diagnoses patients with melioidosis within hours, rather than days, meaning they can receive the correct antibiotics faster.
Developing the world's first lung cancer vaccine
26 March 2024
Researchers at the Nuffield Department of Medicine, the Francis Crick Institute and University College London have been granted £1.7 million of funding from Cancer Research UK and the CRIS Cancer Foundation to develop a lung cancer vaccine. The group includes Professor Tim Elliott, Kidani Professor of Immuno-oncology at NDM.
CMD partners with Ono Pharmaceutical Co for translational research
25 March 2024
The Centre for Medicines Discovery (CMD) at NDM, has recently partnered with Ono Pharmaceutical Co (Ono) to validate and develop novel targets in a bid to discover innovative medicines.
Blog: Advancing tuberculosis research and elimination strategies
22 March 2024
In this blog, Dr Marco Polo Peralta, a senior scientist at NDM’s Jenner Institute provides insight into his research work on tuberculosis and shares how he thinks the 2030 TB elimination goal can be achieved.
New Pandemic PACT research programme launched
21 March 2024
The Pandemic Sciences Institute at NDM, in collaboration with the global coalition of health research funders GloPID-R and UKCDR, has launched a new research programme including an interactive platform to track and analyse over $7 billion in global pandemic research funding.
New bronchoscopy facility expands capacity for respiratory trials
15 March 2024
The Oxford Experimental Medicine Clinical Research Facility hosted by the Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences has expanded its capability to undertake research bronchoscopies. The facility welcomed its first volunteers as part of the Oxford Airways Study to help understand the causes of asthma.
Antimalarial treatments more likely to fail in children with acute malnutrition
13 March 2024
A new study led by researchers from NDM’s Infectious Diseases Data Observatory (IDDO) analysed data from over 11,000 young children, and found that children with acute malnutrition across Africa and Asia have a higher risk of treatment failure and malaria reinfection, despite getting the best currently available and recommended malaria treatment.
UK’s first registry to be set up for those at risk of type 1 diabetes
11 March 2024
Researchers from the Oxford BRC and other collaborating organisations have received funding to set up a UK registry for children and adults who are at risk of type 1 diabetes and have tested positive for diabetes autoantibodies.
Dr Suwarti’s leadership inspires growth at OUCRU Indonesia
8 March 2024
Dr Suwarti (Atie) began her journey with OUCRU Indonesia in 2018 as an awardee of the OUCRU Young Scientist Fellowship programme, when she embarked on a research journey into leptospirosis, a neglected tropical disease. Her curiosity and commitment to improving health outcomes have seen her research interests expand to the molecular diagnostic of Tuberculosis, Covid-19, and HIV.
Research team receives $25m Cancer Grand Challenges award
7 March 2024
A global, interdisciplinary team of researchers, including the Centre for Medicines Discovery’s Professor Frank von Delft, has been selected to receive a Cancer Grand Challenges award of up to $25m over five years to tackle the solid tumours in children challenge. The Cancer Grand Challenges PROTECT team is led by Professor Stefan Pfister of the Hopp Children's Cancer Center in Heidelberg.