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Researchers have reported the results of the first randomised clinical trial to test a novel strategy. The approach involves waking up and then killing the ‘sleeping’ HIV that is hiding in the body using an experimental approach known as ‘kick and kill’.
Medical Grand Rounds
The Medical Grand Rounds are the key educational meetings for consultants, juniors and medical students. Presentations revolve around clinical cases and are followed by lively, educational discussion. All clinical and academic staff and students welcome.
Autoimmune diseases
Autoimmune diseases, where the body's defence systems turn on itself, are chronic and can be devastating to people's lives. Our podcasts on autoimmune conditions detail research in NDM on some of these conditions, including MS, spondyloarthritis and inflammatory bowel disease, as well as the biological mechanisms underpinning autoimmunity itself.
HIV
HIV is one of the worst epidemics in human history, and has had a devastating impact on populations worldwide. Our HIV podcasts describe the leading efforts by NDM researchers to develop new treatments and possible vaccines for HIV, as well as to understand and prevent its transmission, to help reduce the global HIV disease burden and improve outcomes for patients worldwide.
Genetics
We are all products of our genes, and Genetics is a major focus of NDM research. Our podcasts on genetics look at a variety of projects, including the study of some common and less-common inherited afflictions, as well as the effects our genes can have on disease susceptibility and the efficacy of treatment. Moreover, NDM researchers lead in studying the genetic variation within and between human populations, to understand the similarities and differences between us all.
Malaria
Malaria is an endemic disease in much of the world, and is a major contributor to child and infant mortality in many countries. Our malaria podcasts describe efforts by NDM clinicians and scientists, in Oxford and around the world, to treat and prevent malaria, including vaccine development, parasitology, and improved treatment for severe malaria, with the aim to lessen the disease burden on some of the world's most vulnerable people.
Pandemics and vaccines
Vaccines save millions of lives each year; however, some of the world's worst diseases are still difficult to prevent. Our series of podcasts on Epidemics and Vaccines detail the research within NDM to combat diseases such as hepatitis, influenza and tuberculosis, through development of novel vaccines and vaccine delivery mechanisms and strategies. Developing countries and vulnerable populations are a particular focus of some of this work.
Structural biology
NDM celebrated the International Year of Crystallography. Our documentary series Revolutionary Biology explains how the field of structural biology has developed over the past 100 years, Oxford’s involvement in that development, and where we go from here!
Global Health
Translational research in NDM has a truly worldwide impact, with scientists and clinicians investigating epidemiology, treatment, and prevention of disease on a global scale. Our podcasts on Global Health illuminate this work, and discuss research conducted in Oxford and around the world to better understand and manage emerging and endemic diseases.
Translational and clinical medicine
Translational and Clinical Medicine is the ongoing effort to bring basic science from the bench to the patient, as well as to elucidate safety and effectiveness of the medicines on which we depend. The NDM podcasts on translational and clinical medicine detail our work in this wide-ranging field, from the identification and design of new medicines to clinical trials and trial design and regulation.